SCHEMBL5850508

SCHEMBL5850508

S=P(Cl)(Oc1ccc(Cl)cc1)Oc1ccc(Cl)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.58
KMT2A Q03164 2/20 0.58
SMN1; SMN2 Q16637 1/20 0.42
HPGD P15428 1/20 0.41
LMNA P02545 4/20 0.40
CYP2A6 P11509 1/20 0.40
MAOA P21397 1/20 0.39
MAOB P27338 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.38
CYP1A2 P05177 1/20 0.37
CYP2C9 P11712 1/20 0.37
CYP2C19 P33261 1/20 0.37
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
CA9 Q16790 1/20 0.37
STS P08842 3/20 0.35
NPSR1 Q6W5P4 2/20 0.34
HTT P42858 1/20 0.34
ALDH1A1 P00352 1/20 0.34
POLB P06746 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL789906 0.85 MEN1 (0.52) MEN1KMT2ASMN1; SMN2HPGDLMNA
SCHEMBL10591842 0.82 MEN1 (0.54) MEN1KMT2ASMN1; SMN2HPGDLMNA
SCHEMBL11671535 0.82 TDP1 (0.46) MEN1KMT2ASMN1; SMN2HPGDL3MBTL1
SCHEMBL11441985 0.81 MEN1 (0.48) MEN1KMT2ASMN1; SMN2HPGDLMNA
SCHEMBL11778541 0.79 MEN1 (0.57) MEN1KMT2ASMN1; SMN2HPGDLMNA
SCHEMBL11744582 0.78 MEN1 (0.50) MEN1KMT2ASMN1; SMN2HPGDLMNA
SCHEMBL11805977 0.78 CA1 (0.52) MEN1KMT2ASMN1; SMN2HPGDLMNA
SCHEMBL5822931 0.78 MEN1 (0.50) MEN1KMT2ASMN1; SMN2HPGDLMNA
SCHEMBL5850244 0.78 CYP3A4 (0.54) MEN1KMT2ALMNACA1CA2
SCHEMBL11663573 0.78 MEN1 (0.50) MEN1KMT2ASMN1; SMN2HPGDLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7153901-B2 Low viscosity flame retardants are the reaction product of a mixed ester of tetrabromophthalic acid with diethylene glycol and propylene glycol with an acid anhydride, organic phosphate, or organic chlorophosphate; minimizing visible scorching of the flexible polyurethane foam during its production ALBEMARLE CORPORATION (US) 2006-12-26 US disclosed
EP-1685176-A2 FLAME RETARDANT, ADDITIVE COMPOSITIONS, AND FLAME RETARDANT POLYURETHANES ALBEMARLE CORPORATION (US) 2006-08-02 EP disclosed
WO-2005052018-A2 FLAME RETARDANT, ADDITIVE COMPOSITIONS, AND FLAME RETARDANT POLYURETHANES ALBEMARLE CORPORATION (US) 2005-06-09 WO disclosed
US-20050113495-A1 Flame retardant, additive compositions, and flame retardant polyurethanes ALBEMARLE CORPORATION 2005-05-26 US disclosed
US-3984348-A O,O-BIS(ARYL)AMIDO-THIOPHOSPHATES AMERICAN CYANAMID COMPANY (US) 1976-10-05 US disclosed
US-3957798-A LIGHT STABILIZERS, POLYOLEFINS AMERICAN CYANAMID COMPANY (US) 1976-05-18 US disclosed