Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL789906 | 0.81 | MEN1 (0.52) | MEN1KMT2ACYP1A2CYP2C19CYP2C9 | |
| SCHEMBL5850508 | 0.81 | MEN1 (0.58) | MEN1KMT2ACYP1A2CYP2C19CYP2C9 | |
| SCHEMBL10591842 | 0.78 | MEN1 (0.54) | MEN1KMT2ACYP1A2CYP2C19CYP2C9 | |
| SCHEMBL11776578 | 0.77 | MEN1 (0.44) | MEN1KMT2ACYP1A2CYP2C19CYP2C9 | |
| SCHEMBL11477739 | 0.76 | LMNA (0.55) | MEN1KMT2ACYP1A2CYP2C19CYP2C9 | |
| SCHEMBL5822931 | 0.74 | MEN1 (0.50) | MEN1KMT2ACYP1A2CYP2C19CYP2C9 | |
| SCHEMBL11744582 | 0.74 | MEN1 (0.50) | MEN1KMT2ACYP1A2CYP2C19CYP2C9 | |
| SCHEMBL11663573 | 0.74 | MEN1 (0.50) | MEN1KMT2ACYP1A2CYP2C19CYP2C9 | |
| SCHEMBL11177722 | 0.74 | MEN1 (0.61) | MEN1KMT2ACYP1A2CYP2C19CYP2C9 | |
| SCHEMBL11671535 | 0.74 | TDP1 (0.46) | MEN1KMT2ACYP1A2CYP2C19CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4188382-A | Thiazolinyl (thiazolyl) phosphonamidates and phosphoramidates pesticidal and herbicidal compositions based thereon | Vsesojuzny Nauchno, et al. (SU) | 1980-02-12 | — | — | US | disclosed |