SCHEMBL5850539

SCHEMBL5850539

O=P(Cl)(OCCCl)OCCCl

nearest known ligand 0.63

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.63
TP53 P04637 2/20 0.35
TDP1 Q9NUW8 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11879963 0.97 ALDH1A1 (0.60) ALDH1A1TP53TDP1
SCHEMBL11172731 0.84
SCHEMBL8460588 0.81
SCHEMBL26896 0.78 ALDH1A1 (1.00) ALDH1A1TP53TDP1
SCHEMBL499601 0.75 ALDH1A1 (0.94) ALDH1A1TP53
Hydrochloric Acid SCHEMBL21956045 0.75 ALDH1A1 (0.94) ALDH1A1TP53
SCHEMBL17333232 0.75 ALDH1A1 (0.63) ALDH1A1TP53
SCHEMBL11419113 0.75 ALDH1A1 (0.55) ALDH1A1TP53TDP1
SCHEMBL3298770 0.73
SCHEMBL4906432 0.73 ALDH1A1 (0.60) ALDH1A1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-3987129-A PROCESS FOR PREPARING BIS(2-HALOALKYL) PHOSPHORO-HALIDATES OLIN CORPORATION (US) 1976-10-19 US claimed
EP-4744667-A2 EFFICIENT AND SCALABLE SYNTHESES OF NICOTINOYL RIBOSIDES AND REDUCED NICOTINOYL RIBOSIDES, MODIFIED DERIVATIVES THEREOF, PHOSPHORYLATED ANALOGS THEREOF, ADENYLYL DINUCLEOTIDE CONJUGATES THEREOF, AND NOVEL CRYSTALLINE FORMS THEREOF The Queen's University Of Belfast (GB) 2026-05-20 EP disclosed
US-20250163093-A1 EFFICIENT AND SCALABLE SYNTHESES OF NICOTINOYL RIBOSIDES AND REDUCED NICOTINOYL RIBOSIDES, MODIFIED DERIVATIVES THEREOF, PHOSPHORYLATED ANALOGS THEREOF, ADENYLYL DINUCLEOTIDE CONJUGATES THEREOF, AND NOVEL CRYSTALLINE FORMS THEREOF THE QUEEN'S UNIVERSITY OF BELFAST (GB) 2025-05-22 US disclosed
CN-110662542-B Nicotinoyl nucleosides and reduced nicotinoyl nucleosides, modified derivatives thereof, phosphorylated analogs thereof, adenosine dinucleotide conjugates thereof, and efficient and scalable synthesis of novel crystalline forms thereof 英国贝尔法斯特女王大学 2025-04-08 CN disclosed
CN-119320417-A Nicotinoyl nucleosides and reduced nicotinoyl nucleosides, modified derivatives thereof, phosphorylated analogs, adenosine dinucleotide conjugates, and efficient and scalable synthesis of novel crystalline forms 英国贝尔法斯特女王大学 2025-01-17 CN disclosed
US-12195494-B2 Efficient and scalable syntheses of nicotinoyl ribosides and reduced nicotinoyl ribosides, modified derivatives thereof, phosphorylated analogs thereof, adenylyl dinucleotide conjugates thereof, and novel crystalline forms thereof THE QUEEN'S UNIVERSITY OF BELFAST (GB) 2025-01-14 US disclosed
US-20230391815-A1 EFFICIENT AND SCALABLE SYNTHESES OF NICOTINOYL RIBOSIDES AND REDUCED NICOTINOYL RIBOSIDES, MODIFIED DERIVATIVES THEREOF, PHOSPHORYLATED ANALOGS THEREOF, ADENYLYL DINUCLEOTIDE CONJUGATES THEREOF, AND NOVEL CRYSTALLINE FORMS THEREOF THE QUEEN'S UNIVERSITY OF BELFAST (GB) 2023-12-07 US disclosed
US-11345720-B2 Efficient and scalable syntheses of nicotinoyl ribosides and reduced nicotinoyl ribosides, modified derivatives thereof, phosphorylated analogs thereof, adenylyl dinucleotide conjugates thereof, and novel crystalline forms thereof THE QUEEN'S UNIVERSITY OF BELFAST (GB) 2022-05-31 US disclosed
US-20220106350-A1 EFFICIENT AND SCALABLE SYNTHESES OF NICOTINOYL RIBOSIDES AND REDUCED NICOTINOYL RIBOSIDES, MODIFIED DERIVATIVES THEREOF, PHOSPHORYLATED ANALOGS THEREOF, ADENYLYL DINUCLEOTIDE CONJUGATES THEREOF, AND NOVEL CRYSTALLINE FORMS THEREOF THE QUEEN'S UNIVERSITY OF BELFAST (GB) 2022-04-07 US disclosed
CN-107846883-A The solvent-free phosphorylation of selectivity 可劳迈戴斯有限公司 2018-03-27 CN disclosed
US-RE30887-E HALOGENATED PHOSPHATE ESTERS OLIN CORPORATION (US) 1982-03-23 US disclosed
EP-0000132-B1 HALOGEN-SUBSTITUTED ESTERS OF PHOSPHOROUS ACID, POLYMERIC COMPOSITIONS CONTAINING THEM AS REACTIVE FLAME RETARDANTS Velsicol Chemical Corporation (US) 1981-08-05 EP disclosed
US-4281097-A USED IN POLYESTERS AND POLYURETHANES VELSICOL CHEMICAL CORPORATION (US) 1981-07-28 US disclosed
US-4242479-A CATALYST OF ALUMINUM TRIHALIDE, ORGANOSILOXANE COMPOUND OR ETHER, MAGNESIUM ALCOHOLATE, TITANIUM-HALOGEN AND ORGANOALUMINUM COMPOUNDS SHOWA YUKA KABUSHIKI KAISHA (JP) 1980-12-30 US disclosed
US-4212757-A Peroxygen bleaching and compositions therefor FMC CORPORATION (US) 1980-07-15 US disclosed
US-4180636-A MAGNESIUM HALIDE, TITANIUM COMPOUND ELECTRON DONOR COMPOUND, TRIALKYL ALUMINUM CATALYST SHOWA DENKO KABUSHIKI KAISHA (JP) 1979-12-25 US disclosed
EP-0000132-A1 Halogen-substituted esters of phosphorous acid, polymeric compositions containing them as reactive flame retardants Velsicol Chemical Corporation (US) 1979-01-10 EP disclosed
US-4133846-A FIREPROOFING POLYURETHANES AND POLYESTER VELSICOL CHEMICAL CORPORATION (US) 1979-01-09 US disclosed
US-3992488-A REDUCES COMBUSTIBILITY OF COTTON FABRICS OLIN CORPORATION (US) 1976-11-16 US disclosed
US-3987129-A PROCESS FOR PREPARING BIS(2-HALOALKYL) PHOSPHORO-HALIDATES OLIN CORPORATION (US) 1976-10-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250163093-A1 EFFICIENT AND SCALABLE SYNTHESES OF NICOTINOYL RIBOSIDES AND REDUCED NICOTINOYL RIBOSIDES, MODIFIED DERIVATIVES THEREOF, PHOSPHORYLATED ANALOGS THEREOF, ADENYLYL DINUCLEOTIDE CONJUGATES THEREOF, AND NOVEL CRYSTALLINE FORMS THEREOF NAPRT, NAMPT, CD38 ALDH1A1 2757/4885TP53 3698/4885TDP1 629/4885
US-11345720-B2 Efficient and scalable syntheses of nicotinoyl ribosides and reduced nicotinoyl ribosides, modified derivatives thereof, phosphorylated analogs thereof, adenylyl dinucleotide conjugates thereof, and novel crystalline forms thereof NAPRT, NAMPT, CD38 ALDH1A1 2769/4885TP53 3710/4885TDP1 636/4885
US-20220106350-A1 EFFICIENT AND SCALABLE SYNTHESES OF NICOTINOYL RIBOSIDES AND REDUCED NICOTINOYL RIBOSIDES, MODIFIED DERIVATIVES THEREOF, PHOSPHORYLATED ANALOGS THEREOF, ADENYLYL DINUCLEOTIDE CONJUGATES THEREOF, AND NOVEL CRYSTALLINE FORMS THEREOF NAPRT, NAMPT, CD38 ALDH1A1 2769/4885TP53 3710/4885TDP1 636/4885
US-12195494-B2 Efficient and scalable syntheses of nicotinoyl ribosides and reduced nicotinoyl ribosides, modified derivatives thereof, phosphorylated analogs thereof, adenylyl dinucleotide conjugates thereof, and novel crystalline forms thereof NAPRT, NAMPT, CD38 ALDH1A1 2757/4885TP53 3698/4885TDP1 629/4885
US-20230391815-A1 EFFICIENT AND SCALABLE SYNTHESES OF NICOTINOYL RIBOSIDES AND REDUCED NICOTINOYL RIBOSIDES, MODIFIED DERIVATIVES THEREOF, PHOSPHORYLATED ANALOGS THEREOF, ADENYLYL DINUCLEOTIDE CONJUGATES THEREOF, AND NOVEL CRYSTALLINE FORMS THEREOF NAPRT, NAMPT, CD38 ALDH1A1 2757/4885TP53 3698/4885TDP1 629/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.