Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 6/20 | 0.47 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.44 |
| ▸ | LAP3 | P28838 | 2/20 | 0.38 |
| ▸ | METAP1 | P53582 | 1/20 | 0.38 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.38 |
| ▸ | S1PR4 | O95977 | 4/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5850876 | 0.83 | FDPS (0.40) | FDPSSMPD1FAAHCYP3A4L3MBTL1 | |
| SCHEMBL3823543 | 0.83 | FDPS (0.50) | FDPSSMPD1LAP3METAP1S1PR2 | |
| SCHEMBL3010735 | 0.83 | SMPD1 (0.57) | FDPSSMPD1LAP3METAP1S1PR2 | |
| SCHEMBL8555956 | 0.79 | — | — | |
| SCHEMBL3814007 | 0.79 | CYP3A4 (0.45) | FDPSSMPD1CYP3A4L3MBTL1 | |
| SCHEMBL3813612 | 0.78 | SMPD1 (0.55) | FDPSSMPD1LAP3S1PR2S1PR1 | |
| SCHEMBL3822629 | 0.78 | CYP3A4 (0.41) | FDPSSMPD1FAAHCYP3A4L3MBTL1 | |
| SCHEMBL4947189 | 0.78 | SMPD1 (0.66) | FDPSSMPD1LAP3S1PR2S1PR1 | |
| SCHEMBL29790872 | 0.77 | SMPD1 (0.46) | FDPSSMPD1LAP3METAP1S1PR2 | |
| SCHEMBL27809466 | 0.77 | FDPS (0.44) | FDPSSMPD1LAP3METAP1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7153901-B2 | Low viscosity flame retardants are the reaction product of a mixed ester of tetrabromophthalic acid with diethylene glycol and propylene glycol with an acid anhydride, organic phosphate, or organic chlorophosphate; minimizing visible scorching of the flexible polyurethane foam during its production | ALBEMARLE CORPORATION (US) | 2006-12-26 | — | — | US | disclosed |
| EP-1685176-A2 | FLAME RETARDANT, ADDITIVE COMPOSITIONS, AND FLAME RETARDANT POLYURETHANES | ALBEMARLE CORPORATION (US) | 2006-08-02 | — | — | EP | disclosed |
| WO-2005052018-A2 | FLAME RETARDANT, ADDITIVE COMPOSITIONS, AND FLAME RETARDANT POLYURETHANES | ALBEMARLE CORPORATION (US) | 2005-06-09 | — | — | WO | disclosed |
| US-20050113495-A1 | Flame retardant, additive compositions, and flame retardant polyurethanes | ALBEMARLE CORPORATION | 2005-05-26 | — | — | US | disclosed |