SCHEMBL585143

SCHEMBL585143

CCCC(=O)OC(C)c1ccccc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 1/20 0.51
KDM4E B2RXH2 2/20 0.50
MAPT P10636 1/20 0.50
FFAR1 O14842 1/20 0.45
ALDH1A1 P00352 3/20 0.43
TP53 P04637 1/20 0.43
HSD17B10 Q99714 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
TSHR P16473 2/20 0.43
GPR139 Q6DWJ6 1/20 0.43
LPAR1 Q92633 1/20 0.42
CES2 O00748 1/20 0.42
CES1 P23141 1/20 0.42
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
RECQL P46063 1/20 0.41
LTB4R Q15722 1/20 0.40
LTB4R2 Q9NPC1 1/20 0.40
CYP1A2 P05177 1/20 0.40
CYP3A4 P08684 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5693685 1.00 HCAR2 (0.51) HCAR2KDM4EMAPTFFAR1ALDH1A1
SCHEMBL6242067 1.00 HCAR2 (0.51) HCAR2KDM4EMAPTFFAR1ALDH1A1
Methane SCHEMBL28580094 0.98 HCAR2 (0.50) HCAR2KDM4EMAPTFFAR1ALDH1A1
SCHEMBL28249424 0.95 HCAR2 (0.47) HCAR2KDM4EMAPTFFAR1ALDH1A1
SCHEMBL11461421 0.91 HCAR2 (0.56) HCAR2KDM4EMAPTFFAR1ALDH1A1
SCHEMBL873119 0.90 KDM4E (0.53) HCAR2KDM4EMAPTFFAR1ALDH1A1
SCHEMBL6467147 0.88 LMNA (0.54) HCAR2KDM4EMAPTALDH1A1TP53
SCHEMBL1054349 0.87 HCAR2 (0.53) HCAR2KDM4EMAPTFFAR1ALDH1A1
SCHEMBL8638934 0.87 LMNA (0.57) MAPTALDH1A1TP53TSHRCES2
SCHEMBL10766988 0.87 LMNA (0.57) MAPTALDH1A1TP53TSHRCES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 288 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025051371-A1 A FRAGRANCE PASTILLE SYMRISE AG (DE) 2025-03-13 WO claimed
WO-2025045353-A1 A FRAGRANCE POD SYMRISE AG (DE) 2025-03-06 WO claimed
WO-2025045354-A1 A FRAGRANCE TABLET SYMRISE AG (DE) 2025-03-06 WO claimed
CN-117897055-A Method for reducing abnormal odor 奇华顿股份有限公司 2024-04-16 CN claimed
CN-117396589-A Oral care flavor and assessment method for improving pleasure status 奇华顿股份有限公司 2024-01-12 CN claimed
CN-117396591-A Fragrance and evaluation method for improving happy state 奇华顿股份有限公司 2024-01-12 CN claimed
US-20220364016-A1 PERFUME OIL MIXTURE SYMRISE AG (DE) 2022-11-17 US claimed
CN-115247192-A Enzymatic preparation technology of acyl/aroyl coenzyme A 中国医学科学院药物研究所 2022-10-28 CN claimed
CN-115078573-A Method for predicting quality grade of soft type white spirit base liquor 江苏洋河酒厂股份有限公司 2022-09-20 CN claimed
EP-4025675-A1 A PERFUME OIL MIXTURE Symrise AG (DE) 2022-07-13 EP claimed
CN-101386724-A Application of vegetable oil, ink compound and high boiling point solvent water-scraped without set-off intaglio ink composition GUANBAO FAN (CN) 2009-03-18 CN claimed
EP-1697386-B1 ACTIVE INGREDIENT-RELEASING CYCLIC SILOXANES GEN ELECTRIC (US) 2007-10-10 EP claimed
CN-1893910-A Cyclic siloxane compositions for active ingredient release GEN ELECTRIC (US) 2007-01-10 CN claimed
EP-1716159-A2 CYCLIC SILOXANE COMPOSITIONS FOR THE RELEASE OF ACTIVE INGREDIENTS General Electronic Company (US) 2006-11-02 EP claimed
EP-1697386-A1 ACTIVE INGREDIENT-RELEASING CYCLIC SILOXANES General Electric Company A Corporation of the State of New York (US) 2006-09-06 EP claimed
US-20060166857-A1 4,8-Dimethyl-7-nonen-2-one and 4,8-dimethylnonan-2-one used as perfumes SYMRISE GMBH & CO. KG (DE) 2006-07-27 US claimed
WO-2005066187-A1 ACTIVE INGREDIENT-RELEASING CYCLIC SILOXANES GENERAL ELECTRIC COMPANY (US) 2005-07-21 WO claimed
WO-2005066186-A2 CYCLIC SILOXANE COMPOSITIONS FOR THE RELEASE OF ACTIVE INGREDIENTS GENERAL ELECTRIC COMPANY (US) 2005-07-21 WO claimed
US-20050136021-A1 Active-releasing cyclic siloxanes MOMENTIVE PERFORMANCE MATERIALS INC. 2005-06-23 US claimed
US-20050136022-A1 Cyclic siloxane compositions for the release of active ingredients MOMENTIVE PERFORMANCE MATERIALS INC. 2005-06-23 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050136022-A1 Cyclic siloxane compositions for the release of active ingredients F9, RPL39, ECPAS HCAR2 1140/4885KDM4E 94/4885MAPT 815/4885
US-20050136021-A1 Active-releasing cyclic siloxanes F9, RPL39, ALDH16A1 HCAR2 579/4885KDM4E 79/4885MAPT 1453/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.