SCHEMBL5851920

SCHEMBL5851920

Cc1ccc(OP(=O)(Cl)Oc2ccccc2)cc1

nearest known ligand 0.57

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.57
TSHR P16473 1/20 0.57
MEN1 O00255 7/20 0.56
KMT2A Q03164 7/20 0.56
LMNA P02545 2/20 0.56
NPSR1 Q6W5P4 1/20 0.54
MAPT P10636 1/20 0.51
ALDH1A1 P00352 2/20 0.50
HPGD P15428 2/20 0.49
SRC P12931 1/20 0.47
HCRTR1 O43613 1/20 0.46
HTT P42858 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
L3MBTL1 Q9Y468 2/20 0.45
TDP1 Q9NUW8 1/20 0.45
KDM4E B2RXH2 1/20 0.45
HSP90AA1 P07900 1/20 0.45
GAA P10253 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1913721 0.92 TSHR (0.67) CYP3A4TSHRMEN1KMT2ALMNA
SCHEMBL122230 0.87 SRC (0.58) MEN1KMT2ALMNANPSR1HPGD
Water SCHEMBL7889250 0.85 SRC (0.56) MEN1KMT2ALMNANPSR1HPGD
Triphenyl Phosphate SCHEMBL27323542 0.83 CYP3A4 (0.83) CYP3A4TSHRMEN1KMT2ALMNA
SCHEMBL35597 0.83 CYP3A4 (0.83) CYP3A4TSHRMEN1KMT2ALMNA
Triphenyl Phosphate SCHEMBL4087814 0.83 CYP3A4 (0.83) CYP3A4TSHRMEN1KMT2ALMNA
SCHEMBL9657737 0.83 CYP3A4 (0.83) CYP3A4TSHRMEN1KMT2ALMNA
SCHEMBL381595 0.83 CYP3A4 (0.83) CYP3A4TSHRMEN1KMT2ALMNA
SCHEMBL11795872 0.83 LMNA (0.50) CYP3A4TSHRMEN1KMT2ALMNA
SCHEMBL11433934 0.82 CYP3A4 (0.59) CYP3A4TSHRMEN1KMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7153901-B2 Low viscosity flame retardants are the reaction product of a mixed ester of tetrabromophthalic acid with diethylene glycol and propylene glycol with an acid anhydride, organic phosphate, or organic chlorophosphate; minimizing visible scorching of the flexible polyurethane foam during its production ALBEMARLE CORPORATION (US) 2006-12-26 US disclosed
US-4144290-A Production of bromoaryl chlorophosphates BAYER AKTIENGESELLSCHAFT (DE) 1979-03-13 US disclosed
US-3965220-A AMINE CATALYST MONSANTO COMPANY (US) 1976-06-22 US disclosed