Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 15/20 | 0.63 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.63 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.63 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.63 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4698472 | 0.87 | OPRM1 (0.72) | OPRM1KCNH2OPRD1OPRK1 | |
| SCHEMBL5852064 | 0.82 | OPRM1 (0.57) | OPRM1KCNH2OPRD1OPRK1 | |
| SCHEMBL4698578 | 0.81 | OPRM1 (0.74) | OPRM1KCNH2OPRD1OPRK1 | |
| SCHEMBL18091489 | 0.78 | OPRM1 (0.65) | OPRM1KCNH2OPRD1OPRK1 | |
| SCHEMBL18091488 | 0.78 | OPRM1 (0.65) | OPRM1KCNH2OPRD1OPRK1 | |
| SCHEMBL4698127 | 0.78 | OPRM1 (1.00) | OPRM1KCNH2OPRD1OPRK1 | |
| SCHEMBL4700444 | 0.75 | OPRM1 (0.85) | OPRM1KCNH2OPRD1OPRK1 | |
| Cp-866087 SCHEMBL16292952 | 0.75 | OPRM1 (1.00) | OPRM1KCNH2OPRD1OPRK1 | |
| Cp-866087 SCHEMBL4697312 | 0.75 | OPRM1 (1.00) | OPRM1KCNH2OPRD1OPRK1 | |
| SCHEMBL4697868 | 0.75 | OPRM1 (0.77) | OPRM1KCNH2OPRD1OPRK1GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7049335-B2 | 3-azabicyclo[3.1.0]hexane derivatives | PFIZER INC. (US) | 2006-05-23 | — | — | US | claimed |