Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR3 | Q9UBY5 | 15/20 | 0.54 |
| ▸ | LPAR2 | Q9HBW0 | 12/20 | 0.54 |
| ▸ | LPAR1 | Q92633 | 9/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | LPAR6 | P43657 | 4/20 | 0.37 |
| ▸ | LPAR4 | Q99677 | 4/20 | 0.37 |
| ▸ | LPAR5 | Q9H1C0 | 4/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | CDC25A | P30304 | 1/20 | 0.35 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.35 |
| ▸ | AKT1 | P31749 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8044305 | 0.98 | LPAR3 (0.57) | LPAR3LPAR2LPAR1CYP3A4LPAR6 | |
| SCHEMBL5850473 | 0.98 | LPAR3 (0.57) | LPAR3LPAR2LPAR1CYP3A4LPAR6 | |
| SCHEMBL5852208 | 0.98 | LPAR3 (0.57) | LPAR3LPAR2LPAR1CYP3A4LPAR6 | |
| SCHEMBL8060068 | 0.93 | CYP3A4 (0.46) | LPAR3LPAR2LPAR1CYP3A4 | |
| SCHEMBL258312 | 0.85 | LPAR3 (0.62) | LPAR3LPAR2LPAR1CYP3A4LPAR6 | |
| SCHEMBL40063 | 0.83 | LPAR3 (0.67) | LPAR3LPAR2LPAR1CYP3A4LPAR6 | |
| SCHEMBL258534 | 0.83 | LPAR3 (0.67) | LPAR3LPAR2LPAR1CYP3A4LPAR6 | |
| SCHEMBL258188 | 0.83 | LPAR3 (0.67) | LPAR3LPAR2LPAR1CYP3A4LPAR6 | |
| SCHEMBL284021 | 0.83 | LPAR3 (0.67) | LPAR3LPAR2LPAR1CYP3A4LPAR6 | |
| SCHEMBL258270 | 0.83 | LPAR3 (0.67) | LPAR3LPAR2LPAR1CYP3A4LPAR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7153901-B2 | Low viscosity flame retardants are the reaction product of a mixed ester of tetrabromophthalic acid with diethylene glycol and propylene glycol with an acid anhydride, organic phosphate, or organic chlorophosphate; minimizing visible scorching of the flexible polyurethane foam during its production | ALBEMARLE CORPORATION (US) | 2006-12-26 | — | — | US | disclosed |
| EP-1685176-A2 | FLAME RETARDANT, ADDITIVE COMPOSITIONS, AND FLAME RETARDANT POLYURETHANES | ALBEMARLE CORPORATION (US) | 2006-08-02 | — | — | EP | disclosed |
| WO-2005052018-A2 | FLAME RETARDANT, ADDITIVE COMPOSITIONS, AND FLAME RETARDANT POLYURETHANES | ALBEMARLE CORPORATION (US) | 2005-06-09 | — | — | WO | disclosed |
| US-20050113495-A1 | Flame retardant, additive compositions, and flame retardant polyurethanes | ALBEMARLE CORPORATION | 2005-05-26 | — | — | US | disclosed |
| US-6018067-A | UPGRADING A CRUDE DIHYDROCARBYLTHIOPHOSPHATE PRODUCT CONTAMINATED WITH A DIHYDROCARBYLPOLYSULFIDE AND/OR A DIHYDROCARBYLCHLOROPHOSPHATE, BY TREATING WITH HYPOCHLORITE SOLUTION AND SEPARATING AN AQUEOUS PHASE FROM THE PRODUCT | ALBEMARLE CORPORATION (US) | 2000-01-25 | — | — | US | disclosed |
| US-5955626-A | Process of purifying dihydrocarbylchlorothiophosphates | ALBEMARLE CORPORATION (US) | 1999-09-21 | — | — | US | disclosed |
| EP-0731805-A1 | AMIDES OF ACIDS OF PHOSPHORUS FOR THE EXTRACTION OF METALS | ZENECA LIMITED (GB) | 1996-09-18 | — | — | EP | disclosed |
| WO-1995015329-A1 | AMIDES OF ACIDS OF PHOSPHORUS FOR THE EXTRACTION OF METALS | ZENECA LIMITED (GB) | 1995-06-08 | — | — | WO | disclosed |