Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.65 |
| ▸ | MAPT | P10636 | 3/20 | 0.65 |
| ▸ | USP2 | O75604 | 3/20 | 0.65 |
| ▸ | CASP1 | P29466 | 3/20 | 0.65 |
| ▸ | MEN1 | O00255 | 2/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.65 |
| ▸ | TP53 | P04637 | 1/20 | 0.65 |
| ▸ | POLB | P06746 | 1/20 | 0.65 |
| ▸ | HTT | P42858 | 1/20 | 0.65 |
| ▸ | CASP7 | P55210 | 1/20 | 0.65 |
| ▸ | ATM | Q13315 | 1/20 | 0.65 |
| ▸ | PRSS1 | P07477 | 9/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL34160 | 0.94 | GAA (0.71) | GAAKDM4EALDH1A1MAPTUSP2 | |
| Hydrochloric Acid SCHEMBL1426505 | 0.92 | GAA (0.75) | GAAKDM4EALDH1A1MAPTUSP2 | |
| Hydrochloric Acid SCHEMBL3421592 | 0.92 | GAA (0.75) | GAAKDM4EALDH1A1MAPTUSP2 | |
| Hydrochloric Acid SCHEMBL30994761 | 0.92 | GAA (0.75) | GAAKDM4EALDH1A1MAPTUSP2 | |
| SCHEMBL455466 | 0.92 | GAA (0.62) | GAAKDM4EALDH1A1MAPTUSP2 | |
| SCHEMBL11218926 | 0.90 | GAA (0.71) | GAAKDM4EALDH1A1MAPTUSP2 | |
| Hydrochloric Acid SCHEMBL11225965 | 0.90 | GAA (0.66) | GAAKDM4EALDH1A1MAPTUSP2 | |
| SCHEMBL11225049 | 0.88 | GAA (0.69) | GAAKDM4EALDH1A1MAPTUSP2 | |
| Hydrochloric Acid SCHEMBL11233537 | 0.88 | GAA (0.75) | GAAKDM4EALDH1A1MAPTUSP2 | |
| SCHEMBL11221321 | 0.88 | GAA (0.69) | GAAKDM4EALDH1A1MAPTUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1286953-B1 | (P-AMINO-HYDROXYPHENYL)-ACRYLAMIDE DERIVATIVES AND DYES CONTAINING SAID COMPOUNDS | WELLA AG (DE) | 2004-02-18 | — | — | EP | claimed |
| US-6342078-B1 | OXIDATION COLOR DYES FOR HAIR WITH METAPHENYLENEDIAMINE COUPLERS | L'OREAL, S. A. (FR) | 2002-01-29 | — | — | US | claimed |
| US-6997961-B2 | N-heteroarylmethyl-m-phenylenediamine derivatives-containing dyes for keratin fibers and novel n-heteroarylmethyl-m-phenylenediamine derivatives | WELLA AG (DE) | 2006-02-14 | — | — | US | disclosed |
| US-6749644-B2 | DEVELOPER AND COUPLER; WIDE RANGE OF DIFFERENT COLOR SHADES FROM BLOND TO BROWN, PURPLE, VIOLET AND EVEN BLUE AND BLACK; INTENSITY | WELLA AKTIENGESELLSCHAFT (DE) | 2004-06-15 | — | — | US | disclosed |
| US-20020166180-A1 | 2-hydroxy-5-amino-biphenyl-derivatives and oxidative hair colouring agents containing said compounds | HFC PRESTIGE INTERNATIONAL OPERATIONS SWITZERLAND SÀRL (CH) | 2002-11-14 | — | — | US | disclosed |
| US-6379400-B1 | DYEING FIBERS, SOLVENT OF WATER OR ALCOHOL AND NITROANILINE DYE | WELLA AKTIENGESELLSCHAFT (DE) | 2002-04-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020166180-A1 | 2-hydroxy-5-amino-biphenyl-derivatives and oxidative hair colouring agents containing said compounds | AHR, KRT18, HMOX2 | GAA 4440/4885KDM4E 396/4885ALDH1A1 20/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.