SCHEMBL5852571

SCHEMBL5852571

O=C(N[Zr](Cl)(Cl)(c1cccc2c1Cc1ccccc1-2)[SiH](c1ccccc1)c1ccccc1)c1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 2/20 0.39
RAB9A P51151 2/20 0.39
KDM4E B2RXH2 3/20 0.36
LMNA P02545 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
HTR2B P41595 2/20 0.34
HTR7 P34969 1/20 0.34
SRD5A2 P31213 2/20 0.34
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
ALDH1A1 P00352 2/20 0.33
MAPT P10636 2/20 0.33
HPGD P15428 2/20 0.33
DRD2 P14416 1/20 0.33
DRD4 P21917 1/20 0.33
DRD3 P35462 1/20 0.33
MAPK14 Q16539 2/20 0.33
CYP1A2 P05177 2/20 0.33
PPARG P37231 1/20 0.33
CYP2C9 P11712 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5854179 0.91 SMN1; SMN2 (0.43) NPC1RAB9ALMNAMEN1KMT2A
SCHEMBL5855114 0.90 RAB9A (0.37) NPC1RAB9AKDM4ELMNATDP1
SCHEMBL5853125 0.88 MAPK14 (0.39) NPC1RAB9ALMNAMEN1KMT2A
SCHEMBL5855645 0.87 RAB9A (0.48) NPC1RAB9AKDM4EHTR2BHTR7
SCHEMBL5854947 0.87 RAB9A (0.42) NPC1RAB9AKDM4ELMNATDP1
SCHEMBL5854180 0.87 RAB9A (0.39) NPC1RAB9AKDM4EHTR2BHTR7
SCHEMBL5854305 0.86 NPC1 (0.38) NPC1RAB9ALMNAHTR2BHTR7
SCHEMBL5853793 0.85 RAB9A (0.37) NPC1RAB9AKDM4ELMNAHTR2B
SCHEMBL5856940 0.84 RAB9A (0.40) NPC1RAB9AKDM4ELMNAHTR2B
SCHEMBL5853420 0.84 RAB9A (0.40) NPC1RAB9AHTR2BHTR7MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7037989-B2 Copolymers of ethylene and/or α-olefins and vicinally disubstituted olefins EXXONMOBIL CHEMICAL PATENTS INC. (US) 2006-05-02 US disclosed
WO-2004106394-A1 COPOLYMERS OF ETHYLENE AND/OR α-OLEFINS AND VICINALLY DISUBSTITUTED OLEFINS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2004-12-09 WO disclosed
US-20040242814-A1 COPOLYMERS OF ETHYLENE AND/OR ALPHA-OLEFINS AND VICINALLY DISUBSTITUTED OLEFINS EXXONMOBIL CHEMICAL PATENTS INC. 2004-12-02 US disclosed