SCHEMBL5852744

SCHEMBL5852744

C[SiH](C)[Ti](Cl)(Cl)(NC(=O)c1ccccc1)c1cccc2c1Cc1ccccc1-2

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 3/20 0.42
NPC1 O15118 2/20 0.42
HTR2B P41595 2/20 0.35
HTR7 P34969 1/20 0.35
SRD5A2 P31213 2/20 0.35
KDM4E B2RXH2 5/20 0.34
MAPT P10636 3/20 0.34
ALDH1A1 P00352 2/20 0.34
LMNA P02545 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
HPGD P15428 1/20 0.34
DRD2 P14416 1/20 0.34
DRD4 P21917 1/20 0.34
DRD3 P35462 1/20 0.34
MEN1 O00255 3/20 0.33
KMT2A Q03164 3/20 0.33
HSP90AA1 P07900 2/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
PNMT P11086 1/20 0.33
CYP1A2 P05177 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5855448 0.90 SMN1; SMN2 (0.40) RAB9ANPC1MAPTALDH1A1LMNA
SCHEMBL5854722 0.89 RAB9A (0.39) RAB9ANPC1HTR2BHTR7SRD5A2
SCHEMBL5853729 0.88 NPC1 (0.40) RAB9ANPC1HTR2BHTR7SRD5A2
SCHEMBL5853371 0.88 MAPK14 (0.38) RAB9ANPC1ALDH1A1MEN1KMT2A
SCHEMBL5856710 0.87 RAB9A (0.51) RAB9ANPC1HTR2BHTR7SRD5A2
SCHEMBL5854704 0.86 RAB9A (0.41) RAB9ANPC1HTR2BHTR7KDM4E
SCHEMBL5854014 0.85 NPC1 (0.40) RAB9ANPC1HTR2BHTR7ALDH1A1
SCHEMBL5855782 0.84 NPC1 (0.42) RAB9ANPC1HTR2BHTR7MAPT
SCHEMBL5853480 0.84 RAB9A (0.42) RAB9ANPC1HTR2BHTR7KDM4E
SCHEMBL5852362 0.84 RAB9A (0.39) RAB9ANPC1HTR2BHTR7KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7037989-B2 Copolymers of ethylene and/or α-olefins and vicinally disubstituted olefins EXXONMOBIL CHEMICAL PATENTS INC. (US) 2006-05-02 US disclosed
WO-2004106394-A1 COPOLYMERS OF ETHYLENE AND/OR α-OLEFINS AND VICINALLY DISUBSTITUTED OLEFINS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2004-12-09 WO disclosed
US-20040242814-A1 COPOLYMERS OF ETHYLENE AND/OR ALPHA-OLEFINS AND VICINALLY DISUBSTITUTED OLEFINS EXXONMOBIL CHEMICAL PATENTS INC. 2004-12-02 US disclosed