SCHEMBL5852903

SCHEMBL5852903

CCCCCCCCCCCC(=O)N[Hf](Cl)(Cl)(C1C=Cc2ccccc21)[SiH](C)C

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CETP P11597 1/20 0.39
EPHX2 P34913 1/20 0.38
SOAT1 P35610 3/20 0.38
SOAT2 O75908 1/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
EP300 Q09472 1/20 0.37
NPC1 O15118 3/20 0.36
LMNA P02545 2/20 0.36
RAB9A P51151 2/20 0.36
P2RX7 Q99572 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
POLB P06746 2/20 0.36
ASAH1 Q13510 2/20 0.36
GLA P06280 1/20 0.36
MAPK1 P28482 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
SPHK2 Q9NRA0 1/20 0.35
SPHK1 Q9NYA1 1/20 0.35
GAA P10253 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5853905 1.00 CETP (0.39) CETPEPHX2SOAT1SOAT2MEN1
SCHEMBL5855507 0.99 NPC1 (0.37) CETPEPHX2SOAT1SOAT2MEN1
SCHEMBL5853176 0.96 CETP (0.36) CETPMEN1KMT2ANPC1LMNA
SCHEMBL5853662 0.91 MAPK1 (0.35) MEN1KMT2ANPC1LMNARAB9A
SCHEMBL5854309 0.89 EPHX2 (0.39) CETPEPHX2SOAT1SOAT2MEN1
SCHEMBL5852540 0.89 EPHX2 (0.39) CETPEPHX2SOAT1SOAT2MEN1
SCHEMBL5853445 0.87 EPHX2 (0.37) CETPEPHX2SOAT1SOAT2MEN1
SCHEMBL5852586 0.86 SMN1; SMN2 (0.31) MEN1KMT2ASMN1; SMN2MAPK1
SCHEMBL5853443 0.84 ALDH1A1 (0.34) CETPEPHX2MEN1KMT2ASMN1; SMN2
SCHEMBL5852802 0.81 MEN1 (0.41) MEN1KMT2ALMNASMN1; SMN2POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7037989-B2 Copolymers of ethylene and/or α-olefins and vicinally disubstituted olefins EXXONMOBIL CHEMICAL PATENTS INC. (US) 2006-05-02 US disclosed
WO-2004106394-A1 COPOLYMERS OF ETHYLENE AND/OR α-OLEFINS AND VICINALLY DISUBSTITUTED OLEFINS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2004-12-09 WO disclosed
US-20040242814-A1 COPOLYMERS OF ETHYLENE AND/OR ALPHA-OLEFINS AND VICINALLY DISUBSTITUTED OLEFINS EXXONMOBIL CHEMICAL PATENTS INC. 2004-12-02 US disclosed