Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 20/20 | 0.61 |
| ▸ | CNR1 | P21554 | 3/20 | 0.61 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4000364 | 0.92 | CNR2 (0.61) | CNR2CNR1KCNH2 | |
| SCHEMBL3979588 | 0.88 | CNR2 (0.63) | CNR2CNR1KCNH2 | |
| SCHEMBL584287 | 0.86 | CNR2 (0.64) | CNR2CNR1KCNH2 | |
| SCHEMBL3916403 | 0.84 | CNR2 (0.59) | CNR2CNR1KCNH2 | |
| SCHEMBL3756608 | 0.84 | CNR2 (0.65) | CNR2CNR1KCNH2 | |
| SCHEMBL589032 | 0.84 | CNR2 (0.67) | CNR2CNR1KCNH2 | |
| SCHEMBL4966435 | 0.83 | CNR2 (0.62) | CNR2CNR1KCNH2 | |
| SCHEMBL3915459 | 0.83 | CNR2 (0.64) | CNR2CNR1KCNH2 | |
| SCHEMBL5181670 | 0.82 | CNR2 (0.56) | CNR2CNR1KCNH2 | |
| SCHEMBL3971110 | 0.82 | CNR2 (0.60) | CNR2CNR1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1797077-B1 | BENZIMIDAZOLE DERIVATIVES, COMPOSITIONS CONTAINING THEM, PREPARATION THEREOF AND USES THEREOF I | ASTRAZENECA AB (SE) | 2012-02-15 | — | — | EP | disclosed |