Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 20/20 | 0.59 |
| ▸ | CNR1 | P21554 | 3/20 | 0.59 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3917970 | 0.90 | CNR2 (0.57) | CNR2CNR1KCNH2 | |
| SCHEMBL3930332 | 0.90 | CNR2 (0.58) | CNR2CNR1KCNH2 | |
| SCHEMBL589032 | 0.85 | CNR2 (0.67) | CNR2CNR1KCNH2 | |
| SCHEMBL4966435 | 0.84 | CNR2 (0.62) | CNR2CNR1KCNH2 | |
| SCHEMBL3915459 | 0.84 | CNR2 (0.64) | CNR2CNR1KCNH2 | |
| SCHEMBL585319 | 0.84 | CNR2 (0.61) | CNR2CNR1KCNH2 | |
| SCHEMBL5181670 | 0.83 | CNR2 (0.56) | CNR2CNR1KCNH2 | |
| SCHEMBL584061 | 0.83 | CNR2 (0.64) | CNR2CNR1KCNH2 | |
| SCHEMBL5181920 | 0.83 | CNR2 (0.62) | CNR2CNR1KCNH2 | |
| SCHEMBL3918179 | 0.83 | CNR2 (0.57) | CNR2CNR1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1797078-A4 | COMPOUNDS, COMPOSITIONS CONTAINING THEM, PREPARATION THEREOF AND USES THEREOF III | ASTRAZENECA AB (SE) | 2009-04-01 | — | — | EP | claimed |
| EP-1797078-A1 | COMPOUNDS, COMPOSITIONS CONTAINING THEM, PREPARATION THEREOF AND USES THEREOF III | AstraZeneca AB (SE) | 2007-06-20 | — | — | EP | claimed |
| WO-2006033630-A1 | COMPOUNDS, COMPOSITIONS CONTAINING THEM, PREPARATION THEREOF AND USES THEREOF III | ASTRAZENECA AB (SE) | 2006-03-30 | — | — | WO | claimed |
| EP-1797078-A4 | COMPOUNDS, COMPOSITIONS CONTAINING THEM, PREPARATION THEREOF AND USES THEREOF III | ASTRAZENECA AB (SE) | 2009-04-01 | — | — | EP | disclosed |
| EP-1797078-A1 | COMPOUNDS, COMPOSITIONS CONTAINING THEM, PREPARATION THEREOF AND USES THEREOF III | AstraZeneca AB (SE) | 2007-06-20 | — | — | EP | disclosed |
| WO-2006033630-A1 | COMPOUNDS, COMPOSITIONS CONTAINING THEM, PREPARATION THEREOF AND USES THEREOF III | ASTRAZENECA AB (SE) | 2006-03-30 | — | — | WO | disclosed |