SCHEMBL5853365

SCHEMBL5853365

Cc1ccccc1C(=O)N[Hf](Cl)(Cl)(c1cccc2c1Cc1ccccc1-2)[SiH](c1ccccc1)c1ccccc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 2/20 0.38
RAB9A P51151 2/20 0.38
HTR7 P34969 1/20 0.36
HTR2B P41595 1/20 0.36
DRD2 P14416 2/20 0.35
DRD4 P21917 2/20 0.35
DRD3 P35462 2/20 0.35
MYC P01106 1/20 0.34
HPGD P15428 1/20 0.34
HSP90AA1 P07900 2/20 0.34
ALDH1A1 P00352 2/20 0.33
KMT2A Q03164 2/20 0.33
MEN1 O00255 1/20 0.33
KCNK3 O14649 1/20 0.33
KCNK9 Q9NPC2 1/20 0.33
PPARG P37231 1/20 0.32
CYP2C9 P11712 1/20 0.32
TSHR P16473 1/20 0.32
RECQL P46063 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5853876 0.91 RAB9A (0.39) NPC1RAB9AHTR7HTR2BDRD2
SCHEMBL5853914 0.89 NPC1 (0.40) NPC1RAB9AHTR7HTR2BDRD2
SCHEMBL5855856 0.88 RAB9A (0.37) NPC1RAB9AHTR7HTR2BDRD2
SCHEMBL5853653 0.87 NPC1 (0.36) NPC1RAB9AHTR7HTR2BDRD2
SCHEMBL5852959 0.86 NPC1 (0.39) NPC1RAB9AHTR7HTR2BDRD2
SCHEMBL5853489 0.86 RAB9A (0.37) NPC1RAB9AHTR7HTR2BDRD2
SCHEMBL5855903 0.85 NPC1 (0.48) NPC1RAB9AHTR7HTR2BDRD2
SCHEMBL5854356 0.85 RAB9A (0.37) NPC1RAB9AHTR7HTR2BDRD2
SCHEMBL5854033 0.84 SMN1; SMN2 (0.40) NPC1RAB9AALDH1A1KMT2AMEN1
SCHEMBL5853764 0.82 RAB9A (0.40) NPC1RAB9AHTR7HTR2BDRD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7037989-B2 Copolymers of ethylene and/or α-olefins and vicinally disubstituted olefins EXXONMOBIL CHEMICAL PATENTS INC. (US) 2006-05-02 US disclosed
US-20040242814-A1 COPOLYMERS OF ETHYLENE AND/OR ALPHA-OLEFINS AND VICINALLY DISUBSTITUTED OLEFINS EXXONMOBIL CHEMICAL PATENTS INC. 2004-12-02 US disclosed