⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9548473 | 0.81 | CYP2A6 (0.50) | — | |
| SCHEMBL2829221 | 0.81 | ALDH1A1 (0.50) | — | |
| SCHEMBL29896037 | 0.81 | ALDH1A1 (0.50) | — | |
| Hydrochloric Acid SCHEMBL30967433 | 0.79 | ALDH1A1 (0.48) | — | |
| Hydrochloric Acid SCHEMBL10942983 | 0.79 | ALDH1A1 (0.48) | — | |
| SCHEMBL23183097 | 0.77 | — | — | |
| SCHEMBL272036 | 0.77 | — | — | |
| SCHEMBL12317161 | 0.77 | — | — | |
| SCHEMBL21415461 | 0.77 | — | — | |
| Ethyne SCHEMBL17596309 | 0.77 | ALDH1A1 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160251409-A1 | Targeted Delivery of Factor VIII Proteins to Platelets | NOVO NORDISK AS (DK) | 2016-09-01 | — | — | US | disclosed |
| EP-2417155-B1 | TARGETED DELIVERY OF FACTOR VIII PROTEINS TO PLATELETS | NOVO NORDISK AS (DK) | 2013-06-19 | — | — | EP | disclosed |
| US-20120093840-A1 | TARGETED DELIVERY OF FACTOR VIII PROTEINS TO PLATELETS | NOVO NORDISK A/S (DK) | 2012-04-19 | — | — | US | disclosed |
| EP-2417155-A1 | TARGETED DELIVERY OF FACTOR VIII PROTEINS TO PLATELETS | Novo Nordisk A/S (DK) | 2012-02-15 | — | — | EP | disclosed |
| WO-2010115866-A1 | TARGETED DELIVERY OF FACTOR VIII PROTEINS TO PLATELETS | NOVO NORDISK A/S (DK) | 2010-10-14 | — | — | WO | disclosed |