Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CCR5 | P51681 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | MIF | P14174 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.34 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.34 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | CTSD | P07339 | 1/20 | 0.33 |
| ▸ | CTSE | P14091 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5853851 | 1.00 | LMNA (0.42) | LMNACCR5TAAR1CYP2D6MIF | |
| SCHEMBL5853926 | 0.85 | AOC3 (0.39) | LMNACCR5TRPA1AOC3HTR2A | |
| SCHEMBL5853924 | 0.85 | AOC3 (0.39) | LMNACCR5TRPA1AOC3HTR2A | |
| SCHEMBL10640638 | 0.84 | LMNA (0.42) | LMNACCR5TAAR1CYP2D6MIF | |
| SCHEMBL10640640 | 0.84 | LMNA (0.42) | LMNACCR5TAAR1CYP2D6MIF | |
| SCHEMBL1111815 | 0.83 | LMNA (0.45) | LMNACCR5TAAR1CYP2D6MIF | |
| SCHEMBL5854697 | 0.82 | POLB (0.39) | LMNACYP2D6HTR2ASMN1; SMN2 | |
| SCHEMBL5854693 | 0.82 | POLB (0.39) | LMNACYP2D6HTR2ASMN1; SMN2 | |
| SCHEMBL5852964 | 0.81 | LMNA (0.39) | LMNACCR5TAAR1CYP2D6MIF | |
| SCHEMBL5852961 | 0.81 | LMNA (0.39) | LMNACCR5TAAR1CYP2D6MIF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7037989-B2 | Copolymers of ethylene and/or α-olefins and vicinally disubstituted olefins | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2006-05-02 | — | — | US | disclosed |
| WO-2004106394-A1 | COPOLYMERS OF ETHYLENE AND/OR α-OLEFINS AND VICINALLY DISUBSTITUTED OLEFINS | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2004-12-09 | — | — | WO | disclosed |
| US-20040242814-A1 | COPOLYMERS OF ETHYLENE AND/OR ALPHA-OLEFINS AND VICINALLY DISUBSTITUTED OLEFINS | EXXONMOBIL CHEMICAL PATENTS INC. | 2004-12-02 | — | — | US | disclosed |