Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | PDE2A | O00408 | 2/20 | 0.43 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.43 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | XDH | P47989 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9986418 | 0.91 | CA1 (0.50) | CA1CA2PDE2APDE3BPDE3A | |
| SCHEMBL4084548 | 0.86 | CA1 (0.48) | CA1CA2CA12CA9 | |
| SCHEMBL9985821 | 0.86 | CA1 (0.48) | CA1CA2TDP1KDM4EMAPK1 | |
| SCHEMBL26238276 | 0.83 | CA2 (0.48) | CA1CA2ENPP2 | |
| SCHEMBL29954116 | 0.83 | NR5A1 (0.49) | CA1CA2CA12CA9 | |
| SCHEMBL4748959 | 0.82 | NR5A1 (0.51) | CA1CA2 | |
| SCHEMBL8505542 | 0.82 | NR5A1 (0.51) | CA1CA2 | |
| SCHEMBL4748948 | 0.82 | NR5A1 (0.51) | CA1CA2 | |
| SCHEMBL2559249 | 0.81 | CA1 (0.47) | CA1CA2TDP1KDM4EMAPK1 | |
| SCHEMBL17073984 | 0.81 | TDP1 (0.53) | CA1PDE2APDE3BPDE3AP2RY12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7001648-B2 | Glassy chiral-nematic liquid crystals and optical devices containing same | UNIVERSITY OF ROCHESTER (US) | 2006-02-21 | — | — | US | disclosed |
| US-20050263741-A1 | GLASSY CHIRAL-NEMATIC LIQUID CRYSTALS AND OPTICAL DEVICES CONTAINING SAME | NATIONAL SCIENCE FOUNDATION | 2005-12-01 | — | — | US | disclosed |
| WO-2004083335-A2 | GLASSY CHIRAL-NEMATIC LIQUID CRYSTALS AND OPTICAL DEVICES CONTAINING SAME | UNIVERSITY OF ROCHESTER (US) | 2004-09-30 | — | — | WO | disclosed |