Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 3/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.37 |
| ▸ | TDO2 | P48775 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | AHR | P35869 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.33 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3853939 | 0.75 | TSHR (0.44) | TSHRMAPK1HIF1ATDP1LMNA | |
| SCHEMBL776297 | 0.75 | TSHR (0.38) | TSHRTDP1LMNATP53HPGD | |
| Hydrochloric Acid SCHEMBL11163950 | 0.73 | CYP2C19 (0.36) | TSHRTDP1LMNATP53HPGD | |
| SCHEMBL10672180 | 0.73 | ATM (0.51) | TSHRMAPK1HIF1ATDP1LMNA | |
| SCHEMBL10410615 | 0.71 | ADRB2 (0.50) | TSHRMAPK1HIF1ATDP1LMNA | |
| SCHEMBL12015736 | 0.71 | TSHR (0.48) | TSHRMAPK1HIF1ATDP1LMNA | |
| SCHEMBL28742456 | 0.71 | ADRB2 (0.50) | TSHRMAPK1HIF1ATDP1LMNA | |
| SCHEMBL16234245 | 0.71 | ADRB2 (0.50) | TSHRMAPK1HIF1ATDP1LMNA | |
| SCHEMBL6074846 | 0.71 | IDO1 (0.50) | TSHRMAPK1HIF1ATDP1LMNA | |
| SCHEMBL11040029 | 0.71 | TSHR (0.50) | TSHRMAPK1HIF1ATDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7087764-B2 | Process for producing arylsulfenyl halide | SHIONOGI & CO., LTD. (JP) | 2006-08-08 | — | — | US | disclosed |
| US-20030195363-A1 | Process for producing arylsulfenyl halide | AOKI TSUTOMU (JP) | 2003-10-16 | — | — | US | disclosed |
| EP-1072588-B1 | PROCESS FOR PRODUCING ARYLSULFENYL HALIDE | SHIONOGI & CO (JP) | 2003-07-09 | — | — | EP | disclosed |
| EP-1072588-A1 | PROCESS FOR PRODUCING ARYLSULFENYL HALIDE | SHIONOGI & CO., LTD. (JP) | 2001-01-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030195363-A1 | Process for producing arylsulfenyl halide | ALK, CBR1, CYP1B1 | TSHR 620/4885MAPK1 228/4885HIF1A 1424/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.