SCHEMBL5854283

SCHEMBL5854283

CCCCCCCCCCCCOc1ccc(C)cc1C(N)=O

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.67
LMNA P02545 2/20 0.67
MEN1 O00255 2/20 0.67
KMT2A Q03164 2/20 0.67
NR1I2 O75469 1/20 0.67
CHRM2 P08172 1/20 0.67
CYP3A4 P08684 1/20 0.67
ADRA2A P08913 1/20 0.67
OPRK1 P41145 1/20 0.67
HTR2B P41595 1/20 0.67
SLC6A3 Q01959 1/20 0.67
HDAC6 Q9UBN7 1/20 0.67
SMPD1 P17405 4/20 0.51
PTPN11 Q06124 4/20 0.51
S1PR3 Q99500 1/20 0.51
PTPN1 P18031 1/20 0.48
PTPN6 P29350 1/20 0.48
HTT P42858 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12180298 0.89 MAPT (0.51) MAPTLMNAMEN1KMT2ANR1I2
SCHEMBL9500879 0.87 PTPN11 (0.67) MAPTLMNAMEN1KMT2ANR1I2
SCHEMBL5325696 0.87 PTPN11 (0.67) MAPTLMNAMEN1KMT2ANR1I2
SCHEMBL27518516 0.85 MAPT (0.67) MAPTLMNAMEN1KMT2ANR1I2
Zinc Ion SCHEMBL11771793 0.85 S1PR3 (0.54) MAPTLMNAMEN1KMT2ANR1I2
SCHEMBL11771803 0.85 PTPN11 (0.65) MAPTLMNAMEN1KMT2ANR1I2
SCHEMBL7089316 0.85 MEN1 (0.67) MAPTLMNAMEN1KMT2ANR1I2
SCHEMBL11775746 0.85 PTPN11 (0.64) MAPTLMNAMEN1KMT2ANR1I2
SCHEMBL12972414 0.84 MAPT (0.59) MAPTLMNAMEN1KMT2ANR1I2
SCHEMBL8337247 0.84 MEN1 (0.65) MAPTLMNAMEN1KMT2ANR1I2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7108964-B2 Compound containing an anthranilic acid blocking group EASTMAN KODAK COMPANY (US) 2006-09-19 US disclosed
US-20060051710-A1 Compound containing an anthranilic acid blocking group EASTMAN KODAK COMPANY 2006-03-09 US disclosed