Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.65 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.65 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.65 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 1/20 | 0.65 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.65 |
| ▸ | HTR2B | P41595 | 1/20 | 0.65 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.65 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.65 |
| ▸ | PTPN11 | Q06124 | 4/20 | 0.51 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.50 |
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | THRA | P10827 | 2/20 | 0.47 |
| ▸ | THRB | P10828 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13884693 | 0.94 | MEN1 (0.56) | MEN1NR1I2LMNACHRM2CYP3A4 | |
| SCHEMBL7951291 | 0.90 | HTR2B (0.50) | MEN1NR1I2LMNACHRM2CYP3A4 | |
| SCHEMBL10592254 | 0.87 | PTPN11 (0.66) | MEN1NR1I2LMNACHRM2CYP3A4 | |
| SCHEMBL12505352 | 0.85 | TP53 (0.48) | MEN1NR1I2LMNACHRM2CYP3A4 | |
| SCHEMBL11360893 | 0.85 | PTPN11 (0.50) | MEN1NR1I2LMNACHRM2CYP3A4 | |
| SCHEMBL12505368 | 0.84 | MAPT (0.49) | MEN1NR1I2LMNACHRM2CYP3A4 | |
| SCHEMBL7089316 | 0.84 | MEN1 (0.67) | MEN1NR1I2LMNACHRM2CYP3A4 | |
| SCHEMBL27518516 | 0.84 | MAPT (0.67) | MEN1NR1I2LMNACHRM2CYP3A4 | |
| SCHEMBL5854283 | 0.84 | MAPT (0.67) | MEN1NR1I2LMNACHRM2CYP3A4 | |
| SCHEMBL13108649 | 0.84 | MEN1 (0.57) | MEN1NR1I2LMNACHRM2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004014844-A2 | ARYL AND HETEROARYL COMPOUNDS AND METHODS TO MODULATE COAGULATION | TRANSTECH PHARMA, INC. (US) | 2004-02-19 | — | — | WO | disclosed |