Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | PTGES | O14684 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 7/20 | 0.37 |
| ▸ | CCR8 | P51685 | 2/20 | 0.37 |
| ▸ | EPOR | P19235 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5854351 | 1.00 | TDP1 (0.45) | TDP1LMNAADRA2ACNR1ATM | |
| SCHEMBL23824720 | 0.88 | TDP1 (0.54) | TDP1LMNAADRA2ACNR1ATM | |
| SCHEMBL1527657 | 0.88 | TDP1 (0.54) | TDP1LMNAADRA2ACNR1ATM | |
| SCHEMBL1527655 | 0.88 | TDP1 (0.54) | TDP1LMNAADRA2ACNR1ATM | |
| SCHEMBL8856826 | 0.88 | TDP1 (0.54) | TDP1LMNAADRA2ACNR1ATM | |
| SCHEMBL5854396 | 0.88 | TDP1 (0.54) | TDP1LMNAADRA2ACNR1ATM | |
| SCHEMBL10829249 | 0.87 | TDP1 (0.46) | TDP1LMNAADRA2ACNR1ATM | |
| SCHEMBL8304055 | 0.87 | TDP1 (0.46) | TDP1LMNAADRA2ACNR1ATM | |
| SCHEMBL11592061 | 0.87 | TDP1 (0.46) | TDP1LMNAADRA2ACNR1ATM | |
| SCHEMBL8210825 | 0.86 | TDP1 (0.54) | TDP1LMNAADRA2ACNR1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7009079-B2 | Chiral copper complex and production processes thereof and using the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2006-03-07 | — | — | US | disclosed |