Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 10/20 | 0.40 |
| ▸ | PTGES | O14684 | 1/20 | 0.39 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.39 |
| ▸ | GNA15 | P30679 | 1/20 | 0.38 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | CETP | P11597 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11592061 | 1.00 | TDP1 (0.46) | TDP1LMNAADRA2ACNR1ATM | |
| SCHEMBL10829249 | 1.00 | TDP1 (0.46) | TDP1LMNAADRA2ACNR1ATM | |
| SCHEMBL5854396 | 0.90 | TDP1 (0.54) | TDP1LMNAADRA2ACNR1ATM | |
| SCHEMBL9020889 | 0.90 | TDP1 (0.54) | TDP1LMNAADRA2ACNR1ATM | |
| SCHEMBL1527655 | 0.90 | TDP1 (0.54) | TDP1LMNAADRA2ACNR1ATM | |
| SCHEMBL23824720 | 0.90 | TDP1 (0.54) | TDP1LMNAADRA2ACNR1ATM | |
| SCHEMBL8210825 | 0.90 | TDP1 (0.54) | TDP1LMNAADRA2ACNR1ATM | |
| SCHEMBL8856826 | 0.90 | TDP1 (0.54) | TDP1LMNAADRA2ACNR1ATM | |
| SCHEMBL5043710 | 0.90 | TDP1 (0.54) | TDP1LMNAADRA2ACNR1ATM | |
| SCHEMBL1527657 | 0.90 | TDP1 (0.54) | TDP1LMNAADRA2ACNR1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0555388-B1 | INSECTICIDAL, ACARICIDAL AND FUNGICIDAL AMINOPYRIMIDINES | DU PONT (US) | 1999-01-27 | — | — | EP | disclosed |
| EP-0513046-B1 | ARTHROPODICIDAL PYRAZOLINES, PYRAZOLIDINES AND HYDRAZINES | DU PONT (US) | 1997-07-09 | — | — | EP | disclosed |
| EP-0781768-A1 | Arthropodicidal anilides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1997-07-02 | — | — | EP | disclosed |
| EP-0530264-B1 | ARTHROPODICIDAL TETRAHYDROPYRIDAZINES | DU PONT (US) | 1996-10-23 | — | — | EP | disclosed |
| EP-0565574-B1 | ARTHROPODICIDAL CARBOXANILIDES | DU PONT (US) | 1995-08-02 | — | — | EP | disclosed |
| EP-0365155-B1 | N-sulfenylated and N-acylated pyrazolines | DU PONT (US) | 1995-05-10 | — | — | EP | disclosed |
| EP-0286346-B1 | Insecticidal substituted indazoles | DU PONT (US) | 1994-04-06 | — | — | EP | disclosed |
| EP-0377304-B1 | Substituted semicarbazone arthropodicides | DU PONT (US) | 1994-03-09 | — | — | EP | disclosed |
| EP-0386892-A2 | Arthropodicidal tetrahydrobenzopyranopyrazoles | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1990-09-12 | — | — | EP | disclosed |
| EP-0300692-A1 | Insecticidal pyrazolines | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-01-25 | — | — | EP | disclosed |
| EP-0223521-A2 | Insecticidal and acaricidal phenoxypyridinyl esters and intermediates | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-05-27 | — | — | EP | disclosed |