SCHEMBL585441

SCHEMBL585441

O=C1c2ccccc2C(=O)N1CCCCCCCCCCCCBr

nearest known ligand 0.64

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.64
L3MBTL1 Q9Y468 1/20 0.64
CHRM2 P08172 2/20 0.57
MEN1 O00255 1/20 0.57
CYP1A2 P05177 1/20 0.57
CYP2C19 P33261 1/20 0.57
KMT2A Q03164 1/20 0.57
HDAC8 Q9BY41 3/20 0.57
HDAC3 O15379 2/20 0.57
HDAC4 P56524 2/20 0.57
HDAC1 Q13547 2/20 0.57
HDAC7 Q8WUI4 2/20 0.57
HDAC2 Q92769 2/20 0.57
HDAC10 Q969S8 2/20 0.57
HDAC11 Q96DB2 2/20 0.57
HDAC6 Q9UBN7 2/20 0.57
HDAC9 Q9UKV0 2/20 0.57
HDAC5 Q9UQL6 2/20 0.57
ACHE P22303 4/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL875710 1.00 TDP1 (0.64) TDP1L3MBTL1CHRM2MEN1CYP1A2
SCHEMBL4579011 1.00 TDP1 (0.64) TDP1L3MBTL1CHRM2MEN1CYP1A2
SCHEMBL98805 1.00 TDP1 (0.64) TDP1L3MBTL1CHRM2MEN1CYP1A2
SCHEMBL7515272 1.00 TDP1 (0.64) TDP1L3MBTL1CHRM2MEN1CYP1A2
SCHEMBL876407 1.00 TDP1 (0.64) TDP1L3MBTL1CHRM2MEN1CYP1A2
SCHEMBL4580702 1.00 TDP1 (0.64) TDP1L3MBTL1CHRM2MEN1CYP1A2
SCHEMBL4579395 1.00 TDP1 (0.64) TDP1L3MBTL1CHRM2MEN1CYP1A2
SCHEMBL3986297 1.00 TDP1 (0.64) TDP1L3MBTL1CHRM2MEN1CYP1A2
SCHEMBL6561802 1.00 TDP1 (0.64) TDP1L3MBTL1CHRM2MEN1CYP1A2
SCHEMBL7523852 1.00 TDP1 (0.64) TDP1L3MBTL1CHRM2MEN1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250367166-A1 NEXT GENERATION DIPROVOCIMS THAT ACTIVATE THE INNATE AND ADAPTIVE IMMUNE RESPONSE SCRIPPS RESEARCH INST (US) 2025-12-04 US disclosed
WO-2023212650-A1 NEXT GENERATION DIPROVOCIMS THAT ACTIVATE THE INNATE AND ADAPTIVE IMMUNE RESPONSE THE SCRIPPS RESEARCH INSTITUTE (US) 2023-11-02 WO disclosed
EP-2950151-B1 ELECTROPHOTOGRAPHIC MEMBER, PROCESS CARTRIDGE AND ELECTROPHOTOGRAPHIC IMAGE FORMING APPARATUS CANON KK (JP) 2020-11-11 EP disclosed
US-10305052-B2 Triptycene derivative useful as material for forming self-assembled film, method for manufacturing said triptycene derivative, film using same, method for manufacturing said film, and electronic device using said method JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) 2019-05-28 US disclosed
US-9977353-B2 Electrophotographic member, process cartridge and electrophotographic image forming apparatus CANON KABUSHIKI KAISHA (JP) 2018-05-22 US disclosed
US-9934882-B2 Amine compound and ionic conductive agent, and electroconductive resin composition CANON KABUSHIKI KAISHA (JP) 2018-04-03 US disclosed
CN-105093876-B Electrophotography component, handle box and electrophotographic image-forming apparatus 佳能株式会社 2017-11-28 CN disclosed
WO-2017197056-A1 BROMODOMAIN TARGETING DEGRONIMERS FOR TARGET PROTEIN DEGRADATION C4 THERAPEUTICS, INC. (US) 2017-11-16 WO disclosed
US-20170279058-A1 TRIPTYCENE DERIVATIVE USEFUL AS MATERIAL FOR FORMING SELF-ASSEMBLED FILM, METHOD FOR MANUFACTURING SAID TRIPTYCENE DERIVATIVE, FILM USING SAME, METHOD FOR MANUFACTURING SAID FILM, AND ELECTRONIC DEVICE USING SAID METHOD JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) 2017-09-28 US disclosed
EP-2950151-A1 ELECTROPHOTOGRAPHIC MEMBER, PROCESS CARTRIDGE AND ELECTROPHOTOGRAPHIC IMAGE FORMING APPARATUS Canon Kabushiki Kaisha (JP) 2015-12-02 EP disclosed
EP-0635023-A4 COVALENTLY CROSS-LINKED OLIGONUCLEOTIDES. ISIS PHARMACEUTICALS INC (US) 1996-03-20 EP disclosed
US-5459255-A For incorporation into oligonucleotides, cleaving RNA site specifically ISIS PHARMACEUTICALS, INC. (US) 1995-10-17 US disclosed
WO-1995021184-A1 SUBSTITUTED PURINES AND OLIGONUCLEOTIDE CROSS-LINKING ISIS PHARMACEUTICALS, INC. (US) 1995-08-10 WO disclosed
US-5424451-A Used as cholinesterase activity inhibitors MEDIOLANUM FARMACEUTICI S.P.A. (IT) 1995-06-13 US disclosed
WO-1995014707-A1 N-2 SUBSTITUTED PURINES ISIS PHARMACEUTICALS, INC. (US) 1995-06-01 WO disclosed
EP-0635023-A1 COVALENTLY CROSS-LINKED OLIGONUCLEOTIDES ISIS PHARMACEUTICALS, INC. (US) 1995-01-25 EP disclosed
US-5302593-A Aminoalkylcarbamic esters of eseroline suitable for use as chlorinesterase activity inhibitors MEDIOLANUM FARMACEUTICI S.P.A. (IT) 1994-04-12 US disclosed
EP-0575954-A1 Aminoalkylcarbamic esters of eseroline suitable for use as cholinesterase acitivity inhibitors and relative preparation process MEDIOLANUM FARMACEUTICI S.P.A. (IT) 1993-12-29 EP disclosed
WO-1993018052-A1 COVALENTLY CROSS-LINKED OLIGONUCLEOTIDES ISIS PHARMACEUTICALS, INC. (US) 1993-09-16 WO disclosed
EP-0087564-A1 Specific binding assay method, reagent system and labelled conjugate for use in this method MILES LABORATORIES, INC. (US) 1983-09-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170279058-A1 TRIPTYCENE DERIVATIVE USEFUL AS MATERIAL FOR FORMING SELF-ASSEMBLED FILM, METHOD FOR MANUFACTURING SAID TRIPTYCENE DERIVATIVE, FILM USING SAME, METHOD FOR MANUFACTURING SAID FILM, AND ELECTRONIC DEVICE USING SAID METHOD TET1, SETDB1, SETD2 TDP1 234/4885L3MBTL1 3793/4885CHRM2 1904/4885
US-10305052-B2 Triptycene derivative useful as material for forming self-assembled film, method for manufacturing said triptycene derivative, film using same, method for manufacturing said film, and electronic device using said method TET1, SETDB1, SETD2 TDP1 234/4885L3MBTL1 3793/4885CHRM2 1904/4885
US-20250367166-A1 NEXT GENERATION DIPROVOCIMS THAT ACTIVATE THE INNATE AND ADAPTIVE IMMUNE RESPONSE TLR1, TLR4, TLR3 TDP1 2212/4885L3MBTL1 1207/4885CHRM2 182/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.