⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4970986 | 0.73 | — | — | |
| SCHEMBL11508503 | 0.73 | — | — | |
| SCHEMBL61623 | 0.71 | — | — | |
| SCHEMBL1020320 | 0.70 | — | — | |
| SCHEMBL1019500 | 0.67 | — | — | |
| SCHEMBL14785208 | 0.65 | — | — | |
| SCHEMBL36129 | 0.65 | — | — | |
| SCHEMBL5854484 | 0.63 | — | — | |
| SCHEMBL1019193 | 0.62 | ALDH1A1 (0.32) | — | |
| SCHEMBL3021879 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6722632-B2 | Thermally operated valve containing liquid and filler for automatically modulating the flow of fluids | Kenny, Thomas M. | 2004-04-20 | — | — | US | claimed |
| US-20030025093-A1 | Thermally operated valve containing liquid and filler for automatically modulating the flow of fluids | OGONTZ CORPORATION | 2003-02-06 | — | — | US | claimed |
| US-7098270-B2 | Fluoroelastomer composition | FREUDENBERG-NOK GENERAL PARTNERSHIP (US) | 2006-08-29 | — | — | US | disclosed |
| US-6722632-B2 | Thermally operated valve containing liquid and filler for automatically modulating the flow of fluids | Kenny, Thomas M. | 2004-04-20 | — | — | US | disclosed |
| EP-1400563-A1 | Fluoroelastomer composition | Freudenberg-NOK General Partnership (US) | 2004-03-24 | — | — | EP | disclosed |
| US-20040048983-A1 | FLUOROELASTOMER COMPOSITION | FREUDENBERG-NOK GENERAL PARTNERSHIP | 2004-03-11 | — | — | US | disclosed |
| US-20030025093-A1 | Thermally operated valve containing liquid and filler for automatically modulating the flow of fluids | OGONTZ CORPORATION | 2003-02-06 | — | — | US | disclosed |
| US-4831085-A | CONTAINING (2-OR 3-) BROMOPERFLUOROPROPYL PERFLUOROVINYL ETHER | NIPPON MEKTRON, LIMITED (JP) | 1989-05-16 | — | — | US | disclosed |