Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.50 |
| ▸ | IDO1 | P14902 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CDC7 | O00311 | 1/20 | 0.40 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.40 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.38 |
| ▸ | MGAM | O43451 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SI | P14410 | 1/20 | 0.38 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1146055 | 0.80 | TAAR1 (0.47) | TAAR1IDO1CYP1A2CYP2C19HPGD | |
| SCHEMBL1146052 | 0.80 | TAAR1 (0.46) | TAAR1IDO1CYP1A2CYP2C19HPGD | |
| SCHEMBL10665398 | 0.80 | TAAR1 (0.52) | TAAR1IDO1CYP1A2HPGDKDM4E | |
| SCHEMBL12433151 | 0.80 | HPGD (0.55) | TAAR1IDO1CYP1A2HPGDKDM4E | |
| SCHEMBL31643340 | 0.80 | CYP1A2 (0.60) | CYP1A2HPGDKDM4ETDP1ALDH1A1 | |
| SCHEMBL12433153 | 0.80 | CYP1A2 (0.60) | CYP1A2HPGDKDM4ETDP1ALDH1A1 | |
| SCHEMBL10661344 | 0.78 | IDO1 (0.48) | TAAR1IDO1CYP1A2CYP2C19HPGD | |
| SCHEMBL31643367 | 0.78 | HPGD (0.54) | CYP1A2CYP2C9CYP2C19HPGDKDM4E | |
| SCHEMBL23232393 | 0.77 | CYP2C19 (0.61) | CYP1A2CYP2C19HPGDKDM4ETDP1 | |
| SCHEMBL20738269 | 0.77 | CYP1A1 (0.45) | TAAR1IDO1CYP1A2HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118064908-A | Method for realizing efficient and green electrocatalytic thioether oxidation through tetraminocobalt complex | 大连理工大学 | 2024-05-24 | — | — | CN | disclosed |
| CN-115141814-B | Application of 4-hydroxyacetophenone monooxygenase | 江南大学 | 2023-05-05 | — | — | CN | disclosed |
| CN-112480136-B | Heteroatom-bridged carbazole derivatives and uses thereof | 北京八亿时空液晶科技股份有限公司 | 2022-12-13 | — | — | CN | disclosed |
| CN-112321469-B | Synthetic method of dibenzyl sulfide | 成都理工大学 | 2022-07-12 | — | — | CN | disclosed |
| CN-111517902-B | Aerobic oxidation system containing sulfinic acid, sulfonic acid or derivatives thereof and photo-oxidation promoting method thereof | 清华大学 | 2022-06-14 | — | — | CN | disclosed |
| CN-114522732-A | Preparation and application of chiral titanium-oxygen cluster capable of serving as chiral construction unit | 中南大学 | 2022-05-24 | — | — | CN | disclosed |
| CN-112480136-A | Heteroatom-bridged carbazole derivatives and uses thereof | 北京八亿时空液晶科技股份有限公司 | 2021-03-12 | — | — | CN | disclosed |
| CN-112321469-A | Synthetic method of dibenzyl sulfide | 成都理工大学 | 2021-02-05 | — | — | CN | disclosed |
| CN-111517902-A | Aerobic oxidation system containing sulfinic acid, sulfonic acid or derivatives thereof and photo-oxidation promoting method thereof | 清华大学 | 2020-08-11 | — | — | CN | disclosed |
| US-7022689-B2 | 5-amidino-n-(2-aminophenethyl)-n-hydroxy-benzenesulffonamide derivative, medical composition containing the same, pharmaceutical use thereof and intermediate therefor | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2006-04-04 | — | — | US | disclosed |
| US-20040242455-A1 | 5-amidino-n-(2-aminophenethyl)-n-hydroxy-benzenesulffonamide derivative, medical composition containing the same, pharmaceutical use thereof and intermediate therefor | KISSEI PAHRMACEUTICAL CO., LTD. (JP) | 2004-12-02 | — | — | US | disclosed |
| EP-1415983-A1 | 5-AMIDINO-N-(2-AMINOPHENETHYL)-HYDROXYBENZENESULFONAMIDE DERIVATIVE, MEDICINAL COMPOSITION CONTAINING THE SAME, AND INTERMEDIATE THEREFOR | Kissei Pharmaceutical Co., Ltd. (JP) | 2004-05-06 | — | — | EP | disclosed |
| US-4783562-A | Process for the preparation of trichloromethyl-substituted aromatic compounds, and trichloromethyl-substituted aromatic compounds obtained in this process | BAYER AKTIENGESELLSCHAFT (DE) | 1988-11-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040242455-A1 | 5-amidino-n-(2-aminophenethyl)-n-hydroxy-benzenesulffonamide derivative, medical composition containing the same, pharmaceutical use thereof and intermediate therefor | F11, F2, F7 | TAAR1 4620/4885IDO1 2756/4885CYP1A2 936/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.