Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Palmitic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 known ✓ | P03372 | 1/20 | 0.90 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.90 |
| ▸ | PPARG | P37231 | 7/20 | 0.90 |
| ▸ | PPARD | Q03181 | 7/20 | 0.90 |
| ▸ | PPARA | Q07869 | 7/20 | 0.90 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.90 |
| ▸ | TSHR | P16473 | 4/20 | 0.90 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.90 |
| ▸ | FABP4 | P15090 | 3/20 | 0.90 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.90 |
| ▸ | TLR2 | O60603 | 2/20 | 0.90 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.90 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.90 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.90 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.90 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.90 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.90 |
| ▸ | MEN1 | O00255 | 1/20 | 0.90 |
| ▸ | PDE4A | P27815 | 1/20 | 0.90 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.90 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Stearic Acid SCHEMBL8579196 | 1.00 | GPR84 (0.90) | GPR84PPARGPPARDPPARAHDAC11 | |
| Stearic Acid SCHEMBL60794 | 1.00 | GPR84 (0.90) | GPR84PPARGPPARDPPARAHDAC11 | |
| Myristic Acid SCHEMBL1477647 | 1.00 | GPR84 (0.90) | GPR84PPARGPPARDPPARAHDAC11 | |
| Octanoic Acid SCHEMBL1235050 | 1.00 | GPR84 (0.90) | GPR84PPARGPPARDPPARAHDAC11 | |
| Myristic Acid SCHEMBL502433 | 1.00 | GPR84 (0.90) | GPR84PPARGPPARDPPARAHDAC11 | |
| Myristic Acid SCHEMBL6253364 | 1.00 | GPR84 (0.90) | GPR84PPARGPPARDPPARAHDAC11 | |
| Heptanoate SCHEMBL5078565 | 1.00 | GPR84 (0.90) | GPR84PPARGPPARDPPARAHDAC11 | |
| Heptanoate SCHEMBL385003 | 1.00 | GPR84 (0.90) | GPR84PPARGPPARDPPARAHDAC11 | |
| Octanoic Acid SCHEMBL5136070 | 1.00 | GPR84 (0.90) | GPR84PPARGPPARDPPARAHDAC11 | |
| Decanoic Acid SCHEMBL386211 | 1.00 | GPR84 (0.90) | GPR84PPARGPPARDPPARAHDAC11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 223 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107936186-B | 3D printing wire and preparation method thereof | 中国石油化工股份有限公司 | 2020-06-09 | — | — | CN | claimed |
| CN-108578274-A | A kind of aqueous lipstick and preparation method thereof | 高宝化妆品（中国）有限公司 | 2018-09-28 | — | — | CN | claimed |
| CN-107936444-A | The thermoplastic cellulose of graft modification and Aliphatic Polyester Blends and preparation method | 中国石油化工股份有限公司 | 2018-04-20 | — | — | CN | claimed |
| CN-107938022-A | Fiber and preparation method thereof | 中国石油化工股份有限公司 | 2018-04-20 | — | — | CN | claimed |
| CN-107936187-A | The thermoplastic cellulose of graft modification and Microbe synthesis polyester blend and preparation method | 中国石油化工股份有限公司 | 2018-04-20 | — | — | CN | claimed |
| CN-107936443-A | thermoplastic film and preparation method | 中国石油化工股份有限公司 | 2018-04-20 | — | — | CN | claimed |
| CN-107936186-A | 3D printing silk material and preparation method | 中国石油化工股份有限公司 | 2018-04-20 | — | — | CN | claimed |
| CN-107936442-A | 3D printing silk material and preparation method thereof | 中国石油化工股份有限公司 | 2018-04-20 | — | — | CN | claimed |
| CN-107936501-A | Injection-molded item and preparation method thereof | 中国石油化工股份有限公司 | 2018-04-20 | — | — | CN | claimed |
| CN-107936196-A | Injection-molded item and preparation method | 中国石油化工股份有限公司 | 2018-04-20 | — | — | CN | claimed |
| CN-107793709-A | Thermoplastic cellulose and aliphatic copolyester blend injection-molded item and preparation method | 中国石油化工股份有限公司 | 2018-03-13 | — | — | CN | claimed |
| CN-107793710-A | Thermoplastic cellulose and aliphatic copolyester blend 3D printing silk material and preparation method | 中国石油化工股份有限公司 | 2018-03-13 | — | — | CN | claimed |
| CN-107794593-A | Thermoplastic cellulose and aliphatic aromatic polyester blending fibres and preparation method | 中国石油化工股份有限公司 | 2018-03-13 | — | — | CN | claimed |
| CN-107793708-A | Thermoplastic cellulose and aliphatic aromatic copolyester blends and preparation method | 中国石油化工股份有限公司 | 2018-03-13 | — | — | CN | claimed |
| CN-107793712-A | Thermoplastic cellulose and aliphatic aromatic copolyester blends 3D printing silk material and preparation method | 中国石油化工股份有限公司 | 2018-03-13 | — | — | CN | claimed |
| CN-107793714-A | Thermoplastic film and preparation method | 中国石油化工股份有限公司 | 2018-03-13 | — | — | CN | claimed |
| CN-107793589-A | thermoplastic cellulose and aliphatic copolyester blend and preparation method | 中国石油化工股份有限公司 | 2018-03-13 | — | — | CN | claimed |
| CN-107794597-A | Thermoplastic cellulose and aliphatic copolyester blend fibers and preparation method | 中国石油化工股份有限公司 | 2018-03-13 | — | — | CN | claimed |
| CN-107793711-A | Thermoplastic cellulose and aliphatic aromatic copolyester blends injection-molded item and preparation method | 中国石油化工股份有限公司 | 2018-03-13 | — | — | CN | claimed |
| US-4058122-A | Osmotic system with laminated wall formed of different materials | ALZA CORPORATION (US) | 1977-11-15 | — | — | US | claimed |