Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 3/20 | 0.49 |
| ▸ | CA1 | P00915 | 3/20 | 0.49 |
| ▸ | CA2 | P00918 | 3/20 | 0.49 |
| ▸ | CA7 | P43166 | 3/20 | 0.49 |
| ▸ | CA9 | Q16790 | 3/20 | 0.49 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | GSK3B | P49841 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6030268 | 0.89 | CA12 (0.52) | CA12CA1CA2CA7CA9 | |
| SCHEMBL5721887 | 0.86 | DAO (0.52) | CA12CA1CA2CA7CA9 | |
| SCHEMBL6198736 | 0.82 | CA12 (0.45) | CA12CA1CA2CA7CA9 | |
| SCHEMBL15933864 | 0.80 | MAPT (0.48) | CA12CA1CA2CA7CA9 | |
| SCHEMBL31464162 | 0.80 | DAO (0.57) | CA12CA1CA2CA7CA9 | |
| SCHEMBL9494321 | 0.79 | DAO (0.56) | CA12CA1CA2CA7CA9 | |
| SCHEMBL3659417 | 0.79 | DAO (0.65) | CA12CA1CA2CA7CA9 | |
| SCHEMBL8628954 | 0.77 | DAO (0.53) | CA12CA1CA2CA7CA9 | |
| SCHEMBL938203 | 0.77 | CA12 (0.50) | CA12CA1CA2CA7CA9 | |
| SCHEMBL5737532 | 0.77 | CA12 (0.50) | CA12CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7115595-B2 | Carbapenem compounds | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2006-10-03 | — | — | US | disclosed |
| EP-1357123-B1 | Novel carbapenem, medical and antibacterial comprisisng the same, and uses thereof | SUMITOMO PHARMA (JP) | 2005-11-30 | — | — | EP | disclosed |
| EP-1535924-A1 | Novel carbapenem compounds | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2005-06-01 | — | — | EP | disclosed |
| US-20040063683-A1 | Novel carbapenem compounds | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2004-04-01 | — | — | US | disclosed |
| EP-1357123-A1 | NOVEL CARBAPENEM COMPOUNDS | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2003-10-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040063683-A1 | Novel carbapenem compounds | PTMS, PNISR, LRPPRC | CA12 4291/4885CA1 4780/4885CA2 3656/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.