Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 20/20 | 0.80 |
| ▸ | ITGAV | P06756 | 20/20 | 0.80 |
| ▸ | ITGA2B | P08514 | 20/20 | 0.80 |
| ▸ | ITGB6 | P18564 | 10/20 | 0.77 |
| ▸ | ITGB5 | P18084 | 5/20 | 0.77 |
| ▸ | ITGB1 | P05556 | 3/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2838993 | 0.96 | ITGB3 (0.86) | ITGB3ITGAVITGA2BITGB6ITGB5 | |
| Trifluoroacetic Acid SCHEMBL5859342 | 0.94 | ITGB3 (0.91) | ITGB3ITGAVITGA2BITGB6ITGB5 | |
| Trifluoroacetic Acid SCHEMBL2837525 | 0.93 | ITGB3 (0.79) | ITGB3ITGAVITGA2BITGB6ITGB5 | |
| Trifluoroacetic Acid SCHEMBL2842123 | 0.93 | ITGAV (0.79) | ITGB3ITGAVITGA2BITGB6ITGB5 | |
| Trifluoroacetic Acid SCHEMBL2834556 | 0.93 | ITGB3 (0.81) | ITGB3ITGAVITGA2BITGB6ITGB5 | |
| Trifluoroacetic Acid SCHEMBL5858263 | 0.91 | ITGB3 (0.75) | ITGB3ITGAVITGA2BITGB6ITGB5 | |
| Trifluoroacetic Acid SCHEMBL5857771 | 0.91 | ITGAV (0.93) | ITGB3ITGAVITGA2BITGB6ITGB5 | |
| Trifluoroacetic Acid SCHEMBL2838652 | 0.91 | ITGB3 (0.75) | ITGB3ITGAVITGA2BITGB6ITGB5 | |
| Trifluoroacetic Acid SCHEMBL2842923 | 0.91 | ITGB3 (0.75) | ITGB3ITGAVITGA2BITGB6ITGB5 | |
| SCHEMBL8337741 | 0.91 | ITGAV (0.82) | ITGB3ITGAVITGA2BITGB6ITGB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7119098-B2 | Heteroarylakanoic acids as intergrin receptor antagonists | PHARMACIA CORPORATION (US) | 2006-10-10 | — | — | US | disclosed |
| US-6933304-B2 | Heteroarylalkanoic acids as integrin receptor antagonists | PHARMACIA CORPORATION (US) | 2005-08-23 | — | — | US | disclosed |
| US-20040092497-A1 | Heteroarylakanoic acids as intergrin receptor antagonists | PHARMACIA CORPORATION | 2004-05-13 | — | — | US | disclosed |
| US-20020133023-A1 | Heteroarylalkanoic acids as integrin receptor antagonists | PHARMACIA CORPORATION | 2002-09-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020133023-A1 | Heteroarylalkanoic acids as integrin receptor antagonists | ITGA5, ITGA2B, ITGAV | ITGB3 5/4885ITGAV 3/4885ITGA2B 2/4885 |
| US-20040092497-A1 | Heteroarylakanoic acids as intergrin receptor antagonists | ITGA5, ITGB7, ITGA2B | ITGB3 5/4885ITGAV 13/4885ITGA2B 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.