Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL511319 | 0.89 | SMN1; SMN2 (0.59) | SMN1; SMN2ALDH1A1TDP1TSHRMAPK1 | |
| SCHEMBL124764 | 0.86 | SMN1; SMN2 (0.56) | SMN1; SMN2ALDH1A1TDP1TSHRMAPK1 | |
| SCHEMBL19125483 | 0.85 | SMN1; SMN2 (0.64) | SMN1; SMN2ALDH1A1TDP1TSHRMAPK1 | |
| SCHEMBL11766005 | 0.85 | SMN1; SMN2 (0.59) | SMN1; SMN2ALDH1A1TDP1TSHRMAPK1 | |
| SCHEMBL26117831 | 0.83 | SMN1; SMN2 (0.49) | SMN1; SMN2ALDH1A1TDP1TSHRMAPK1 | |
| SCHEMBL17242253 | 0.82 | SMN1; SMN2 (0.51) | SMN1; SMN2ALDH1A1TDP1TSHRMAPK1 | |
| SCHEMBL6422835 | 0.82 | SMN1; SMN2 (0.51) | SMN1; SMN2ALDH1A1TDP1TSHRMAPK1 | |
| SCHEMBL14550242 | 0.82 | SMN1; SMN2 (0.51) | SMN1; SMN2ALDH1A1TDP1TSHRMAPK1 | |
| SCHEMBL28372728 | 0.82 | SMN1; SMN2 (0.54) | SMN1; SMN2ALDH1A1TDP1TSHRMAPK1 | |
| SCHEMBL27824757 | 0.82 | SMN1; SMN2 (0.54) | SMN1; SMN2ALDH1A1TDP1TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7018463-B2 | Abrasion resistant coating composition | LENS TECHNOLOGY I, LLC (US) | 2006-03-28 | — | — | US | disclosed |
| WO-2005017050-A2 | ABRASION RESISTANT COATING COMPOSITION | LENS TECHNOLOGY I, LLC (US) | 2005-02-24 | — | — | WO | disclosed |
| US-20050020758-A1 | an epoxy-functional silane, a multipodal silane, a strong acid, a solvent, and a condensation catalyst selected from an amine condensation catalyst and an amide condensation catalyst; curable to protective coatings that are transparent or have adjustable refractive index; use on lenses, for example | SDC TECHNOLOGIES, INC. | 2005-01-27 | — | — | US | disclosed |