Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | HCAR2 | Q8TDS4 | 6/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.36 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 5/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9185807 | 1.00 | TSHR (0.56) | TSHRALDH1A1CYP3A4ATMHCAR2 | |
| SCHEMBL5857260 | 1.00 | TSHR (0.56) | TSHRALDH1A1CYP3A4ATMHCAR2 | |
| SCHEMBL8736969 | 0.91 | ATM (0.55) | TSHRALDH1A1CYP3A4ATMHCAR2 | |
| SCHEMBL8736966 | 0.91 | ATM (0.55) | TSHRALDH1A1CYP3A4ATMHCAR2 | |
| SCHEMBL2456633 | 0.87 | TSHR (0.75) | TSHRALDH1A1CYP3A4ATMHCAR2 | |
| SCHEMBL4626289 | 0.86 | TSHR (0.48) | TSHRALDH1A1CYP3A4ATMHCAR2 | |
| SCHEMBL18823427 | 0.85 | TSHR (0.79) | TSHRALDH1A1CYP3A4ATMHCAR2 | |
| SCHEMBL2456155 | 0.85 | TSHR (0.79) | TSHRALDH1A1CYP3A4ATMHCAR2 | |
| SCHEMBL18823424 | 0.85 | TSHR (0.79) | TSHRALDH1A1CYP3A4ATMHCAR2 | |
| SCHEMBL18822946 | 0.85 | TSHR (0.79) | TSHRALDH1A1CYP3A4ATMHCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7038076-B2 | Fumarate derivative, method for producing the same | SHOWA DENKO K.K. (JP) | 2006-05-02 | — | — | US | disclosed |
| EP-1301461-A2 | FUMARATE DERIVATIVE, METHOD FOR PRODUCING THE SAME | Showa Denko K.K. (JP) | 2003-04-16 | — | — | EP | disclosed |
| US-20030060563-A1 | Fumarate derivative, method for producing the same | SHOWA DENKO K.K. (JP) | 2003-03-27 | — | — | US | disclosed |
| US-6376702-B1 | A 1-ALKENYL ETHER | SHOWA DENKO K.K. (JP) | 2002-04-23 | — | — | US | disclosed |
| WO-2002006206-A2 | FUMARATE DERIVATIVE, METHOD FOR PRODUCING THE SAME | SHOWA DENKO K.K. (JP) | 2002-01-24 | — | — | WO | disclosed |