Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | HCAR2 | Q8TDS4 | 5/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8736969 | 1.00 | ATM (0.55) | ATMHCAR2TSHRHPGDALDH1A1 | |
| SCHEMBL5857249 | 0.91 | TSHR (0.56) | ATMHCAR2TSHRHPGDALDH1A1 | |
| SCHEMBL5857260 | 0.91 | TSHR (0.56) | ATMHCAR2TSHRHPGDALDH1A1 | |
| SCHEMBL9185807 | 0.91 | TSHR (0.56) | ATMHCAR2TSHRHPGDALDH1A1 | |
| SCHEMBL16690661 | 0.89 | HCAR2 (0.53) | ATMHCAR2TSHRHPGDALDH1A1 | |
| SCHEMBL22072011 | 0.83 | ATM (0.61) | ATMHCAR2TSHRHPGDALDH1A1 | |
| SCHEMBL9446376 | 0.81 | ALDH1A1 (0.50) | ATMHCAR2TSHRHPGDALDH1A1 | |
| SCHEMBL27619590 | 0.81 | ATM (0.76) | ATMHCAR2TSHRHPGDMAPT | |
| Diethyl Maleate SCHEMBL28137074 | 0.81 | TSHR (0.70) | ATMHCAR2TSHRHPGDALDH1A1 | |
| SCHEMBL19376412 | 0.81 | ATM (0.69) | ATMHCAR2TSHRHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0462183-B1 | FREE-RADICAL CURABLE COMPOSITIONS | DSM NV (NL) | 1998-06-10 | — | — | EP | disclosed |
| US-5334456-A | Containing vinyl ether groups and maleate or fumarate groups | STAMICARBON B.V. (NL) | 1994-08-02 | — | — | US | disclosed |
| EP-0462183-A4 | FREE-RADICAL CURABLE COMPOSITIONS | — | 1992-02-26 | — | — | EP | disclosed |
| EP-0462183-A1 | FREE-RADICAL CURABLE COMPOSITIONS | DSM N.V. (NL) | 1991-12-27 | — | — | EP | disclosed |
| WO-1990010662-A1 | FREE-RADICAL CURABLE COMPOSITIONS | DESOTO, INC. (US) | 1990-09-20 | — | — | WO | disclosed |