Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | COMT | P21964 | 1/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6223353 | 0.80 | SCN2B (0.47) | ALDH1A1CYP1A2HSD17B10NOTUMHTT | |
| SCHEMBL9750954 | 0.75 | HMGCR (0.57) | ALDH1A1LMNAL3MBTL1MEN1KMT2A | |
| SCHEMBL25294091 | 0.74 | SMN1; SMN2 (0.47) | ALDH1A1LMNAATMKDM4ECYP1A2 | |
| SCHEMBL11350307 | 0.74 | KDM4E (0.44) | ALDH1A1KDM4ECYP1A2HPGDBLM | |
| SCHEMBL4886001 | 0.72 | ALDH1A1 (0.56) | ALDH1A1LMNANPSR1ATMMEN1 | |
| SCHEMBL14827205 | 0.70 | ATM (0.47) | ALDH1A1ATMKDM4ECYP1A2HPGD | |
| SCHEMBL3550482 | 0.68 | NOTUM (0.53) | ALDH1A1LMNANPSR1ATMKDM4E | |
| SCHEMBL13817620 | 0.67 | ATM (0.52) | ALDH1A1ATMKDM4ECYP1A2HPGD | |
| SCHEMBL27889164 | 0.66 | ALDH1A1 (0.40) | ALDH1A1LMNAATMKDM4ECYP1A2 | |
| SCHEMBL1779819 | 0.66 | HTT (0.64) | ALDH1A1LMNANPSR1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6989393-B2 | Ccr5 modulators benzimidazoles or benzotriazoles | ASTRAZENECA AB (SE) | 2006-01-24 | — | — | US | disclosed |