Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.45 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.43 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.43 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.43 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.41 |
| ▸ | BRS3 | P32247 | 2/20 | 0.40 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HNF4A | P41235 | 1/20 | 0.39 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5859079 | 0.92 | SMN1; SMN2 (0.59) | FOLH1SMN1; SMN2LTB4R2LPAR1BRS3 | |
| SCHEMBL5859081 | 0.91 | KDM4E (0.47) | FOLH1LTB4R2HTTNR1H4HSD17B10 | |
| SCHEMBL5858995 | 0.90 | PTPN1 (0.43) | FOLH1SMN1; SMN2LTB4R2PTPN1PTPN2 | |
| SCHEMBL5859106 | 0.90 | SMN1; SMN2 (0.48) | FOLH1SMN1; SMN2BRS3CYP2C8 | |
| SCHEMBL5859840 | 0.90 | SMN1; SMN2 (0.44) | FOLH1SMN1; SMN2BRS3HTTPTPN11 | |
| SCHEMBL5859091 | 0.89 | CYP11B1 (0.42) | FOLH1SMN1; SMN2HTT | |
| SCHEMBL5862012 | 0.87 | FOLH1 (0.43) | FOLH1SMN1; SMN2LPAR1HSD17B10 | |
| SCHEMBL5860413 | 0.83 | PDCD1 (0.43) | LTB4R2HTTNR1H4HSD17B10 | |
| SCHEMBL6095819 | 0.82 | CFD (0.50) | SMN1; SMN2HSD17B10 | |
| SCHEMBL6095110 | 0.82 | KLKB1 (0.58) | HNF4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7122543-B2 | Substituted benzoic acid derivatives having NF-κB inhibiting action | DAIICHI SUNTORY PHARMA CO., LTD. (JP) | 2006-10-17 | — | — | US | disclosed |
| EP-1437339-A1 | SUBSTITUTED BENZOIC ACID DERIVATIVES EXHIBITING NF-KAPPA B INHIBITING ACTIVITY | Daiichi Suntory Pharma Co., Ltd. (JP) | 2004-07-14 | — | — | EP | disclosed |
| CN-1505603-A | Substituted benzoic ac id derivatives exhibiting nf-kappab inhibiting activity | ��һ��������ҩ��ʽ���� | 2004-06-16 | — | — | CN | disclosed |
| US-20040039061-A1 | Substituted benzoic acid derivatives exhibiting nf-k b inhibiting activity | DAIICHI ASUBIO PHARMA CO., LTD. (JP) | 2004-02-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040039061-A1 | Substituted benzoic acid derivatives exhibiting nf-k b inhibiting activity | NFKBIA, NFKB2, IKBKB | FOLH1 4276/4885SMN1; SMN2 3711/4885LTB4R2 1376/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.