SCHEMBL5859613

SCHEMBL5859613

C=CCCCC(C(=O)O)C(=O)O

nearest known ligand 0.48

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.48
ABCC4 O15439 1/20 0.48
ALDH1A1 P00352 5/20 0.38
LMNA P02545 2/20 0.38
DDAH1 O94760 1/20 0.37
CPA1 P15085 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
TSHR P16473 2/20 0.36
USP2 O75604 2/20 0.36
CYP3A4 P08684 2/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
HPGD P15428 1/20 0.36
GRIK1 P39086 2/20 0.33
GRIK2 Q13002 2/20 0.33
RECQL P46063 1/20 0.33
ENPEP Q07075 1/20 0.33
LPAR2 Q9HBW0 1/20 0.33
LPAR3 Q9UBY5 1/20 0.33
FAAH O00519 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5856750 0.93 MAPT (0.52) MAPTABCC4ALDH1A1LMNADDAH1
SCHEMBL9495920 0.91 MAPT (0.56) MAPTABCC4ALDH1A1LMNADDAH1
SCHEMBL11512450 0.91 MAPT (0.56) MAPTABCC4ALDH1A1LMNADDAH1
SCHEMBL5369364 0.91 MAPT (0.56) MAPTABCC4ALDH1A1LMNADDAH1
SCHEMBL7088338 0.91 MAPT (0.56) MAPTABCC4ALDH1A1LMNADDAH1
Malonic Acid SCHEMBL6827744 0.84 MAPT (0.41) MAPTABCC4ALDH1A1LMNADDAH1
SCHEMBL5862560 0.84 ABCC4 (0.46) MAPTABCC4ALDH1A1LMNADDAH1
Malonic Acid SCHEMBL16458514 0.83 MAPT (0.53) MAPTABCC4ALDH1A1LMNADDAH1
SCHEMBL3779386 0.83 ABCC4 (0.46) MAPTABCC4ALDH1A1CPA1GRIK1
SCHEMBL3979255 0.81 GPR84 (0.48) MAPTABCC4ALDH1A1LMNAUSP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2006100606-A2 PREPARATION OF BETA-AMINO ACID PRECURSORS VIA INDIUM (III) MEDIATED MARKOVNIKOV ADDITION AND KNOEVENAGEL CONDENSATION WARNER-LAMBERT COMPANY LLC (US) 2006-09-28 WO claimed
US-10240011-B2 Multifunctional curing agents and their use in improving strength of composites containing carbon fibers embedded in polymeric matrix UT-BATTELLE, LLC (US) 2019-03-26 US disclosed
US-20170166712-A1 MULTIFUNCTIONAL CURING AGENTS AND THEIR USE IN IMPROVING STRENGTH OF COMPOSITES CONTAINING CARBON FIBERS EMBEDDED IN POLYMERIC MATRIX UT-BATTELLE, LLC (US) 2017-06-15 US disclosed
US-9617398-B2 Multifunctional curing agents and their use in improving strength of composites containing carbon fibers embedded in a polymeric matrix UT-BATTELLE, LLC (US) 2017-04-11 US disclosed
US-20160102180-A1 MULTIFUNCTIONAL CURING AGENTS AND THEIR USE IN IMPROVING STRENGTH OF COMPOSITES CONTAINING CARBON FIBERS EMBEDDED IN A POLYMERIC MATRIX UT-BATTELLE, LLC (US) 2016-04-14 US disclosed
CN-1898279-A Linear functional copolymers of ethylene with precise and minimum run length distributions and methods of making thereof EXXONMOBIL RES & ENG CO (US) 2007-01-17 CN disclosed
WO-2006100606-A2 PREPARATION OF BETA-AMINO ACID PRECURSORS VIA INDIUM (III) MEDIATED MARKOVNIKOV ADDITION AND KNOEVENAGEL CONDENSATION WARNER-LAMBERT COMPANY LLC (US) 2006-09-28 WO disclosed
US-7060818-B2 Synthesis of macrocyclic tetraamido compounds and new metal insertion process CARNEGIE MELLON UNIVERSITY (US) 2006-06-13 US disclosed
US-5238602-A Electrooptical cells HOFFMANN LA ROCHE INC. (US) 1993-08-24 US disclosed
US-4709030-A 4-ALKENYL OR 2Z-ALKENYL POLYPHENYL COMPOUNDS; ELECTRO-OPTICS HOFFMANN-LA ROCHE INC. (US) 1987-11-24 US disclosed
US-4621901-A ELECTROOPTICS HOFFMANN-LA ROCHE INC. (US) 1986-11-11 US disclosed