Styrene

Styrene

SCHEMBL5859639

C=Cc1ccccc1.N#CCC#N

nearest known ligand 0.64

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Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.64
TSHR P16473 3/20 0.64
MAOB P27338 2/20 0.37
MAOA P21397 1/20 0.37
TP53 P04637 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
NPC1 O15118 1/20 0.35
GAA P10253 1/20 0.35
RAB9A P51151 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
HDAC8 Q9BY41 2/20 0.33
IDO1 P14902 2/20 0.33
MCL1 Q07820 1/20 0.33
PAM P19021 1/20 0.33
CYP2A6 P11509 1/20 0.33
HTT P42858 1/20 0.33
L3MBTL1 Q9Y468 2/20 0.33
KDM4E B2RXH2 1/20 0.33
LMNA P02545 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL27560899 0.84 ALDH1A1 (0.61) ALDH1A1TSHRTP53TDP1HDAC8
Styrene SCHEMBL27725386 0.83 ALDH1A1 (0.74) ALDH1A1TSHRMAOBTP53TDP1
Styrene SCHEMBL28107406 0.83 ALDH1A1 (0.58) ALDH1A1TSHRMAOBMAOATP53
Styrene SCHEMBL27693993 0.83 ALDH1A1 (0.93) ALDH1A1TSHRMAOBMAOATP53
Styrene SCHEMBL1803135 0.83 ALDH1A1 (0.93) ALDH1A1TSHRMAOBMAOATP53
Styrene SCHEMBL570148 0.83
Styrene SCHEMBL27589633 0.82 ALDH1A1 (0.64) ALDH1A1TSHRMAOBMAOATDP1
Styrene SCHEMBL21835101 0.82 ALDH1A1 (0.64) ALDH1A1TSHRMAOBMAOANPC1
Styrene SCHEMBL10431818 0.81 ALDH1A1 (0.70) ALDH1A1TSHRMAOBTP53TDP1
Styrene SCHEMBL3693751 0.81 ALDH1A1 (0.70) ALDH1A1TSHRMAOBTP53TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109081807-A A kind of three substitution 4- aminocarbazole classes and two that prepare replace the method for 1- aminodiphenyls simultaneously [b, d] thiophenes 台州学院 2018-12-25 CN disclosed
US-7074265-B2 Ink jet recording liquid KONICA MINOLTA HOLDINGS, INC. (JP) 2006-07-11 US disclosed
US-20040254262-A1 Ink jet recording liquid KONICA MINOLTA HOLDINGS, INC. (JP) 2004-12-16 US disclosed