Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 1/20 | 0.47 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31477659 | 0.85 | CYP2C19 (0.54) | MAPK1RECQLTDP1NPC1RAB9A | |
| SCHEMBL1573515 | 0.85 | CYP2C19 (0.54) | MAPK1RECQLTDP1NPC1RAB9A | |
| SCHEMBL5862223 | 0.85 | CYP2C19 (0.54) | MAPK1RECQLTDP1NPC1RAB9A | |
| SCHEMBL5862815 | 0.84 | MIF (0.49) | ITGB1ITGA4ALDH1A1MAPTPPARG | |
| SCHEMBL6513375 | 0.84 | HIF1A (0.39) | ITGB1ITGA4MAPK1RECQLTDP1 | |
| SCHEMBL7971106 | 0.83 | CXCR2 (0.40) | ITGB1ITGA4PPARGPPARACA1 | |
| SCHEMBL6517072 | 0.80 | ALDH1A1 (0.48) | ALDH1A1LMNAMAPK1RECQLMAPT | |
| SCHEMBL27159467 | 0.78 | MAPT (0.45) | ALDH1A1LMNAALOX15APEX1MAPK1 | |
| SCHEMBL27159469 | 0.78 | MAPT (0.45) | ALDH1A1LMNAALOX15APEX1MAPK1 | |
| SCHEMBL12834968 | 0.77 | MAPT (0.46) | ALDH1A1LMNAALOX15APEX1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7041667-B1 | CCR5 modulators | PFIZER, INC. (US) | 2006-05-09 | — | — | US | disclosed |
| EP-1013276-A1 | Aminoazacycloalkanes as CCR5 modulators | PFIZER INC. (US) | 2000-06-28 | — | — | EP | disclosed |