Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.41 |
| ▸ | MCHR2 | Q969V1 | 2/20 | 0.41 |
| ▸ | FGFR3 | P22607 | 3/20 | 0.37 |
| ▸ | KDR | P35968 | 3/20 | 0.37 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.37 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.37 |
| ▸ | FGFR4 | P22455 | 2/20 | 0.37 |
| ▸ | BTK | Q06187 | 4/20 | 0.37 |
| ▸ | LTA4H | P09960 | 2/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.37 |
| ▸ | TERT | O14746 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.35 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5860521 | 0.86 | MCHR1 (0.42) | ALDH1A1MCHR1MCHR2BTK | |
| SCHEMBL5862064 | 0.82 | MCHR1 (0.58) | ALDH1A1MCHR1MCHR2TERT | |
| SCHEMBL5862261 | 0.81 | MCHR1 (0.45) | ALDH1A1MCHR1SCN9A | |
| SCHEMBL6348132 | 0.79 | MCHR1 (0.45) | ALDH1A1MCHR1MCHR2BTK | |
| SCHEMBL5860936 | 0.77 | MCHR1 (0.41) | ALDH1A1MCHR1BTK | |
| SCHEMBL6374843 | 0.75 | NPSR1 (0.45) | ALDH1A1MCHR1FGFR3KDRFGFR1 | |
| SCHEMBL5860935 | 0.75 | MCHR1 (0.69) | MCHR1MCHR2 | |
| SCHEMBL5861989 | 0.74 | MCHR1 (0.57) | MCHR1MCHR2TERT | |
| SCHEMBL6380408 | 0.74 | MCHR1 (0.64) | ALDH1A1MCHR1MCHR2LTA4HHRH3 | |
| SCHEMBL5861302 | 0.73 | MCHR1 (0.58) | MCHR1MCHR2TERT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7049307-B2 | Antagonists of melanin concentrating hormone effects on the melanin concentrating hormone receptor | ABBOTT LABORATORIES (US) | 2006-05-23 | — | — | US | claimed |
| US-20050187279-A1 | Antagonists of melanin concentrating hormone effects on the melanin concentrating hormone receptor | ABBVIE INC. | 2005-08-25 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050187279-A1 | Antagonists of melanin concentrating hormone effects on the melanin concentrating hormone receptor | MCHR1, MCHR2, MC1R | ALDH1A1 2303/4885MCHR1 1/4885MCHR2 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.