Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 11/20 | 0.64 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | MCHR2 | Q969V1 | 2/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
| ▸ | MC4R | P32245 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5860819 | 0.87 | MCHR1 (0.68) | MCHR1MCHR2HDAC3HDAC1HDAC2 | |
| SCHEMBL5862152 | 0.83 | MCHR1 (0.47) | MCHR1MCHR2HDAC3HDAC1HDAC2 | |
| SCHEMBL6357972 | 0.82 | MCHR1 (0.47) | MCHR1MCHR2MEN1ALDH1A1KMT2A | |
| SCHEMBL5861286 | 0.82 | MCHR1 (0.44) | MCHR1HDAC3HDAC1HDAC2HRH3 | |
| SCHEMBL5862261 | 0.80 | MCHR1 (0.45) | MCHR1HDAC3HDAC1HDAC2MEN1 | |
| SCHEMBL5862819 | 0.79 | MCHR1 (0.98) | MCHR1MCHR2MEN1ALDH1A1GLA | |
| SCHEMBL5862063 | 0.79 | MCHR1 (0.98) | MCHR1MCHR2MEN1ALDH1A1GLA | |
| SCHEMBL5861327 | 0.78 | MCHR1 (1.00) | MCHR1MCHR2 | |
| SCHEMBL5860926 | 0.76 | MCHR1 (0.81) | MCHR1MCHR2MEN1ALDH1A1GLA | |
| SCHEMBL5860820 | 0.76 | MCHR1 (0.96) | MCHR1MCHR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050137187-A1 | Antagonists of melanin concentrating hormone effects on the melanin concentrating hormone receptor | ABBOTT LABORATORIES | 2005-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050137187-A1 | Antagonists of melanin concentrating hormone effects on the melanin concentrating hormone receptor | MCHR1, MCHR2, MC1R | MCHR1 1/4885CNR2 1318/4885MCHR2 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.