Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | CTSS | P25774 | 2/20 | 0.47 |
| ▸ | CTSL | P07711 | 1/20 | 0.47 |
| ▸ | CTSB | P07858 | 1/20 | 0.47 |
| ▸ | CTSK | P43235 | 1/20 | 0.47 |
| ▸ | ACE | P12821 | 2/20 | 0.45 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.44 |
| ▸ | AKT1 | P31749 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | APP | P05067 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | XBP1 | P17861 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3539282 | 1.00 | ATM (0.48) | ATMCTSSCTSLCTSBCTSK | |
| SCHEMBL5620017 | 1.00 | ATM (0.48) | ATMCTSSCTSLCTSBCTSK | |
| SCHEMBL4042099 | 1.00 | ATM (0.48) | ATMCTSSCTSLCTSBCTSK | |
| SCHEMBL4042106 | 1.00 | ATM (0.48) | ATMCTSSCTSLCTSBCTSK | |
| SCHEMBL5620023 | 1.00 | ATM (0.48) | ATMCTSSCTSLCTSBCTSK | |
| SCHEMBL9296151 | 0.90 | ATM (0.47) | ATMCTSSCTSLCTSBCTSK | |
| SCHEMBL3800004 | 0.89 | ATM (0.47) | ATMCTSSCTSLCTSBCTSK | |
| SCHEMBL4881213 | 0.89 | CTSS (0.39) | ATMCTSSCTSLCTSBCTSK | |
| SCHEMBL4881219 | 0.89 | CTSS (0.39) | ATMCTSSCTSLCTSBCTSK | |
| SCHEMBL6312228 | 0.88 | ATM (0.46) | ATMCTSSCTSLCTSBCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7132568-B2 | Aspartyl protease inhibitors | SUNESIS PHARMACEUTICALS, INC. (US) | 2006-11-07 | — | — | US | disclosed |
| US-20040132782-A1 | Aspartyl protease inhibitors | SUNESIS PHARMACEUTICALS, INC. | 2004-07-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040132782-A1 | Aspartyl protease inhibitors | BACE1, APP, BACE2 | ATM 3804/4885CTSS 59/4885CTSL 69/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.