Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5672726 | 0.85 | HDAC1 (0.34) | HDAC1HDAC2 | |
| SCHEMBL5229466 | 0.84 | — | — | |
| SCHEMBL6293531 | 0.84 | — | — | |
| SCHEMBL6139430 | 0.84 | — | — | |
| SCHEMBL5229660 | 0.76 | IDH1 (0.31) | — | |
| SCHEMBL5227605 | 0.76 | IDH1 (0.31) | — | |
| SCHEMBL5227610 | 0.76 | IDH1 (0.31) | — | |
| SCHEMBL5674587 | 0.73 | MEN1 (0.34) | HDAC1HDAC2 | |
| SCHEMBL5674581 | 0.73 | MEN1 (0.34) | HDAC1HDAC2 | |
| SCHEMBL12600039 | 0.72 | HDAC4 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7001916-B1 | Epothilon derivatives, method for the production and the use thereof as pharmaceuticals | SCHERING, AG (DE) | 2006-02-21 | — | — | US | disclosed |
| EP-1161430-A2 | EPOTHILON DERIVATIVES, METHOD FOR THE PRODUCTION AND THE USE THEREOF AS PHARMACEUTICALS | SCHERING AKTIENGESELLSCHAFT (DE) | 2001-12-12 | — | — | EP | disclosed |
| WO-2000047584-A2 | EPOTHILON DERIVATIVES, METHOD FOR THE PRODUCTION AND THE USE THEREOF AS PHARMACEUTICALS | SCHERING AKTIENGESELLSCHAFT (DE) | 2000-08-17 | — | — | WO | disclosed |