Known targets — ChEMBL curated mechanism
ACHESCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9A
The experimentally established mechanism targets of Gluconic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.77 |
| ▸ | PDE4A | P27815 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Gluconic Acid SCHEMBL21835970 | 1.00 | LMNA (0.77) | LMNAPDE4AL3MBTL1USP2SLCO1B1 | |
| Gluconic Acid SCHEMBL2266761 | 1.00 | LMNA (0.77) | LMNAPDE4AL3MBTL1USP2SLCO1B1 | |
| Gluconic Acid SCHEMBL303216 | 1.00 | LMNA (0.77) | LMNAPDE4AL3MBTL1USP2SLCO1B1 | |
| Gluconic Acid SCHEMBL22653996 | 0.98 | LMNA (0.74) | LMNAPDE4AL3MBTL1USP2SLCO1B1 | |
| Gluconic Acid SCHEMBL22653997 | 0.98 | LMNA (0.74) | LMNAPDE4AL3MBTL1USP2SLCO1B1 | |
| Gluconic Acid SCHEMBL4165311 | 0.98 | LMNA (0.74) | LMNAPDE4AL3MBTL1USP2SLCO1B1 | |
| Gluconic Acid SCHEMBL27096625 | 0.98 | LMNA (0.74) | LMNAPDE4AL3MBTL1USP2SLCO1B1 | |
| Gluconic Acid SCHEMBL377417 | 0.98 | LMNA (0.74) | LMNAPDE4AL3MBTL1USP2SLCO1B1 | |
| Gluconic Acid SCHEMBL14813276 | 0.96 | LMNA (0.84) | LMNAPDE4AL3MBTL1USP2SLCO1B1 | |
| Gluconic Acid SCHEMBL17675382 | 0.96 | LMNA (0.77) | LMNAPDE4AL3MBTL1USP2SLCO1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7138151-B2 | Calcium-fortified acidic beverages | UNILAB PHARMATECH, LTD. (CN) | 2006-11-21 | — | — | US | claimed |
| US-20040101597-A1 | Calcium fortified acidic beverages | UNILAB PHARMATECH, LTD. (CN) | 2004-05-27 | — | — | US | claimed |
| CN-107384319-A | A kind of chemical dust suppressant for mine | 鞍钢集团矿业有限公司 | 2017-11-24 | — | — | CN | disclosed |