Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 14/20 | 0.58 |
| ▸ | FFAR4 | Q5NUL3 | 13/20 | 0.58 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.53 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | PPARD | Q03181 | 1/20 | 0.48 |
| ▸ | PPARA | Q07869 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5860681 | 0.88 | PTGER4 (0.47) | FFAR1FFAR4PTGER4PPARGPPARD | |
| SCHEMBL5860821 | 0.86 | FFAR4 (0.54) | FFAR1FFAR4PTGER4PPARGPPARD | |
| SCHEMBL6166556 | 0.84 | PTGER4 (0.49) | FFAR4PTGER4PPARGPPARDPPARA | |
| SCHEMBL6166560 | 0.80 | PTGER4 (0.47) | FFAR1FFAR4PTGER4PPARGPPARD | |
| SCHEMBL1745359 | 0.80 | FFAR1 (0.63) | FFAR1FFAR4PTGER4PPARGPPARD | |
| SCHEMBL5862763 | 0.79 | PPARD (0.60) | PPARDPPARA | |
| SCHEMBL6165536 | 0.77 | MCHR1 (0.47) | FFAR1FFAR4PTGER4PPARDPPARA | |
| SCHEMBL3905482 | 0.77 | FFAR1 (0.60) | FFAR1FFAR4PTGER4PPARGPPARD | |
| SCHEMBL6165375 | 0.76 | FFAR4 (0.44) | FFAR1FFAR4PTGER4PPARGPPARD | |
| SCHEMBL5860732 | 0.75 | PPARD (0.51) | PTGER4PPARGPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7091237-B2 | Furan and thiophene derivatives that activate human peroxisome proliferator activated receptors | SMITHKLINE BEECHAM CORPORATION (US) | 2006-08-15 | — | — | US | claimed |
| EP-1392674-B1 | FURAN AND THIOPHENE DERIVATIVES THAT ACTIVATE HUMAN PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS | SMITHKLINE BEECHAM CORP (US) | 2005-08-10 | — | — | EP | claimed |
| US-20040157890-A1 | Furan and thiophene derivatives that activate human peroxisome profilerator activated receptors | GLAXO GROUP LIMITED (GB) | 2004-08-12 | — | — | US | claimed |
| US-7091237-B2 | Furan and thiophene derivatives that activate human peroxisome proliferator activated receptors | SMITHKLINE BEECHAM CORPORATION (US) | 2006-08-15 | — | — | US | disclosed |
| EP-1392674-B1 | FURAN AND THIOPHENE DERIVATIVES THAT ACTIVATE HUMAN PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS | SMITHKLINE BEECHAM CORP (US) | 2005-08-10 | — | — | EP | disclosed |
| US-20040157890-A1 | Furan and thiophene derivatives that activate human peroxisome profilerator activated receptors | GLAXO GROUP LIMITED (GB) | 2004-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040157890-A1 | Furan and thiophene derivatives that activate human peroxisome profilerator activated receptors | PPARG, PPARD, PPARA | FFAR1 4/4885FFAR4 5/4885PTGER4 143/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.