Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 8/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.42 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.41 |
| ▸ | PPARD | Q03181 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | PPARA | Q07869 | 2/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5860821 | 0.90 | FFAR4 (0.54) | FFAR4FFAR1PTGER4PPARDPPARG | |
| SCHEMBL5860681 | 0.89 | PTGER4 (0.47) | FFAR4FFAR1PTGER4PPARDPPARG | |
| SCHEMBL3905482 | 0.81 | FFAR1 (0.60) | FFAR4FFAR1PTGER4PPARDPPARG | |
| SCHEMBL5861910 | 0.81 | PPARA (0.47) | PTGER4PPARDPPARA | |
| SCHEMBL5862763 | 0.79 | PPARD (0.60) | PPARDPPARA | |
| SCHEMBL5860732 | 0.78 | PPARD (0.51) | PTGER4PPARDPPARGPPARA | |
| SCHEMBL5861867 | 0.76 | FFAR1 (0.58) | FFAR4FFAR1PTGER4PPARDPPARG | |
| SCHEMBL2305460 | 0.75 | FFAR1 (0.40) | FFAR4FFAR1PPARDPPARGPPARA | |
| SCHEMBL3906291 | 0.75 | PPARD (0.59) | FFAR4FFAR1PPARDPPARGPPARA | |
| SCHEMBL3906389 | 0.73 | PPARD (0.57) | FFAR4FFAR1PPARDPPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1392674-B1 | FURAN AND THIOPHENE DERIVATIVES THAT ACTIVATE HUMAN PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS | SMITHKLINE BEECHAM CORP (US) | 2005-08-10 | — | — | EP | disclosed |