⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2912200 | 0.74 | — | — | |
| SCHEMBL17238980 | 0.70 | — | — | |
| SCHEMBL2303304 | 0.70 | — | — | |
| SCHEMBL17207484 | 0.70 | — | — | |
| SCHEMBL1738125 | 0.68 | HMBS (0.46) | — | |
| SCHEMBL65952 | 0.67 | — | — | |
| SCHEMBL9972520 | 0.67 | — | — | |
| SCHEMBL15269029 | 0.67 | HMBS (0.43) | — | |
| SCHEMBL14793837 | 0.67 | HMBS (0.43) | — | |
| SCHEMBL22674257 | 0.67 | HMBS (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025106863-A1 | LACTAM DERIVATIVES FOR INHIBITING NLRP3 AND USES THEREOF | VENTUS THERAPEUTICS U.S., INC. (US) | 2025-05-22 | — | — | WO | disclosed |
| US-8975235-B2 | Lysophosphatidic acid receptor antagonists | INTERMUNE, INC. (US) | 2015-03-10 | — | — | US | disclosed |
| US-7030145-B2 | Pyridinyl derivatives for the treatment of depression | BRISTOL-MYERS SQUIBB COMPANY (US) | 2006-04-18 | — | — | US | disclosed |
| US-20040209917-A1 | Pyridinyl derivatives for the treatment of depression | HARTZ RICHARD A (US) | 2004-10-21 | — | — | US | disclosed |