Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 5/20 | 0.72 |
| ▸ | CNR1 | P21554 | 1/20 | 0.72 |
| ▸ | CNR2 | P34972 | 1/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | NAAA | Q02083 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7945793 | 0.98 | FAAH (0.75) | FAAHCNR1CNR2ALDH1A1LMNA | |
| SCHEMBL28507254 | 0.98 | FAAH (0.75) | FAAHCNR1CNR2ALDH1A1LMNA | |
| SCHEMBL1042652 | 0.98 | FAAH (0.75) | FAAHCNR1CNR2ALDH1A1LMNA | |
| SCHEMBL8506453 | 0.98 | FAAH (0.75) | FAAHCNR1CNR2ALDH1A1LMNA | |
| SCHEMBL28729643 | 0.96 | FAAH (0.73) | FAAHCNR1CNR2ALDH1A1LMNA | |
| SCHEMBL905446 | 0.94 | FAAH (0.64) | FAAHCNR1CNR2ALDH1A1LMNA | |
| SCHEMBL905488 | 0.94 | FAAH (0.64) | FAAHCNR1CNR2ALDH1A1LMNA | |
| SCHEMBL6828062 | 0.90 | FAAH (0.66) | FAAHCNR1CNR2ALDH1A1LMNA | |
| SCHEMBL29133861 | 0.90 | FAAH (0.66) | FAAHCNR1CNR2ALDH1A1LMNA | |
| SCHEMBL7945794 | 0.89 | FAAH (0.69) | FAAHCNR1CNR2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7060818-B2 | Synthesis of macrocyclic tetraamido compounds and new metal insertion process | CARNEGIE MELLON UNIVERSITY (US) | 2006-06-13 | — | — | US | disclosed |
| WO-2004076425-A1 | IMPROVED SYNTHESIS OF MACROCYCLIC TETRAAMIDO COMPOUNDS AND NEW METAL INSERTION PROCESS | CARNEGIE MELLON UNIVERSITY (US) | 2004-09-10 | — | — | WO | disclosed |
| US-4428887-A | Method of producing mono-substituted terminal diesters | MONSANTO COMPANY (US) | 1984-01-31 | — | — | US | disclosed |