Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | MGAM | O43451 | 1/20 | 0.58 |
| ▸ | SI | P14410 | 1/20 | 0.58 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.58 |
| ▸ | FAAH | O00519 | 5/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL905444 | 0.90 | FAAH (0.53) | GAAMGAMSIMGAM2FAAH | |
| SCHEMBL905443 | 0.90 | FAAH (0.53) | GAAMGAMSIMGAM2FAAH | |
| SCHEMBL905430 | 0.90 | FAAH (0.53) | GAAMGAMSIMGAM2FAAH | |
| SCHEMBL5434703 | 0.84 | GAA (0.62) | GAAMGAMSIMGAM2FAAH | |
| SCHEMBL1206455 | 0.80 | FAAH (0.49) | FAAHCNR1CNR2LMNAALDH1A1 | |
| SCHEMBL29190726 | 0.80 | FAAH (0.49) | GAAMGAMSIMGAM2FAAH | |
| SCHEMBL1979452 | 0.79 | GAA (0.68) | GAAMGAMSIMGAM2LMNA | |
| Malonic Acid Diethyl Ester SCHEMBL9472390 | 0.79 | GAA (0.68) | GAAMGAMSIMGAM2LMNA | |
| SCHEMBL3972639 | 0.79 | GAA (0.56) | GAAMGAMSIMGAM2FAAH | |
| Butane SCHEMBL8404111 | 0.78 | FAAH (0.47) | FAAHCNR1CNR2LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7060818-B2 | Synthesis of macrocyclic tetraamido compounds and new metal insertion process | CARNEGIE MELLON UNIVERSITY (US) | 2006-06-13 | — | — | US | disclosed |