SCHEMBL5862569

SCHEMBL5862569

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nearest known ligand 0.35

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.35
TSHR P16473 1/20 0.35
HSD17B10 Q99714 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27902773 1.00 ALDH1A1 (0.35) ALDH1A1TSHRHSD17B10TDP1
SCHEMBL30114779 1.00 ALDH1A1 (0.35) ALDH1A1TSHRHSD17B10TDP1
SCHEMBL29697226 0.87
SCHEMBL8520966 0.82
SCHEMBL27927667 0.82 ALDH1A1 (0.30) ALDH1A1TSHR
SCHEMBL30213769 0.82 ALDH1A1 (0.30) ALDH1A1TSHR
SCHEMBL7737624 0.82
Acetone SCHEMBL27630934 0.80 SMN1; SMN2 (0.32)
SCHEMBL31324778 0.79 SMN1; SMN2 (0.34)
SCHEMBL20514675 0.79 SMN1; SMN2 (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112601555-A Compositions and methods relating to anti-CD 19 antibody drug conjugates 乐高化学生物科学股份有限公司 2021-04-02 CN claimed
US-20250161462-A1 ENDOSOMAL CLEAVABLE HYDROPHILIC-MASKED CATIONIC CHARGE DELIVERY VEHICLES UNIV CALIFORNIA (US) 2025-05-22 US disclosed
CN-115551537-A Tumor cell vaccine 纽沃进公司 2022-12-30 CN disclosed
CN-115461461-A MiRNA-193a for promoting immunogenic cell death 因特尔纳技术有限公司 2022-12-09 CN disclosed
CN-115315434-A Interleukin 15 fusion proteins and prodrugs and compositions and methods thereof 免疫靶向有限公司 2022-11-08 CN disclosed
CN-114681608-A Combination cancer therapy 戊瑞治疗有限公司 2022-07-01 CN disclosed
CN-114615995-A Combined inhibition of PD-1, TGF beta and ATM and radiotherapy for cancer treatment 阿雷斯贸易股份有限公司 2022-06-10 CN disclosed
CN-114522225-A Arginine deiminase with reduced cross-reactivity to ADI-PEG20 antibodies for cancer treatment 瑞华药业集团 2022-05-24 CN disclosed
CN-114395624-A Methods for treatment and diagnosis of cancer 基因泰克公司 2022-04-26 CN disclosed
CN-114206332-A 2,3, 5-trisubstituted pyrazolo [1,5-A ] pyrimidine compounds 艾库斯生物科学有限公司 2022-03-18 CN disclosed
CN-111566120-A 3'3' cyclic dinucleotides with phosphonate linkages that activate STING transducins 捷克共和国有机化学与生物化学研究所 2020-08-21 CN disclosed
CN-111511754-A 2'3' cyclic dinucleotides with phosphonate linkages that activate STING transducins 捷克共和国有机化学与生物化学研究所 2020-08-07 CN disclosed
CN-111225685-A Combination of PARP inhibitors and PD-1 axis binding antagonists 默克专利股份有限公司 2020-06-02 CN disclosed
CN-105612179-B Monoclonal OLFML-3 antibodies and uses thereof 研究发展基金会 2020-01-21 CN disclosed
CN-110709392-A Isoquinoline as HPK1 inhibitors 豪夫迈·罗氏有限公司 2020-01-17 CN disclosed
CN-110678466-A Naphthyridines as HPK1 inhibitors 豪夫迈·罗氏有限公司 2020-01-10 CN disclosed
US-7037907-B1 Estradiol conjugates and uses thereof THE UNIVERSITY OF MELBOURNE (AU) 2006-05-02 US disclosed
EP-1226154-A4 ESTRADIOL CONJUGATES AND USES THEREOF UNIV MELBOURNE (AU) 2005-03-23 EP disclosed
EP-1226154-A1 ESTRADIOL CONJUGATES AND USES THEREOF THE UNIVERSITY OF MELBOURNE (AU) 2002-07-31 EP disclosed
WO-2001027132-A1 ESTRADIOL CONJUGATES AND USES THEREOF THE UNIVERSITY OF MELBOURNE (AU) 2001-04-19 WO disclosed