Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.56 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.51 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.50 |
| ▸ | HTR1A | P08908 | 3/20 | 0.50 |
| ▸ | DRD2 | P14416 | 3/20 | 0.50 |
| ▸ | HTR2A | P28223 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.50 |
| ▸ | HRH1 | P35367 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | SCN4A | P35499 | 1/20 | 0.50 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.50 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.50 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.50 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2143965 | 0.83 | HDAC8 (0.79) | HDAC8MTNR1AMTNR1BHDAC3HDAC4 | |
| SCHEMBL1366451 | 0.83 | HDAC8 (0.79) | HDAC8MTNR1AMTNR1BHDAC3HDAC4 | |
| SCHEMBL2143907 | 0.81 | HDAC8 (0.76) | HDAC8MTNR1AMTNR1BHDAC3HDAC4 | |
| SCHEMBL5464795 | 0.80 | PIM1 (0.59) | HDAC8MTNR1AMTNR1BPTGS1HTR1A | |
| SCHEMBL5363710 | 0.77 | MTNR1A (0.58) | HDAC8MTNR1AMTNR1BPTGS1HTR1A | |
| SCHEMBL24687436 | 0.77 | HDAC8 (0.69) | HDAC8MAPK1KMT2ACYP3A4HDAC3 | |
| SCHEMBL608494 | 0.77 | HDAC8 (0.69) | HDAC8MAPK1KMT2ACYP3A4HDAC3 | |
| SCHEMBL607416 | 0.77 | HDAC8 (0.69) | HDAC8MAPK1KMT2ACYP3A4HDAC3 | |
| SCHEMBL1366765 | 0.76 | HDAC8 (0.70) | HDAC8MTNR1AMTNR1BPTGS1HTR1A | |
| SCHEMBL5323524 | 0.76 | CES1 (0.53) | HDAC8MTNR1AMTNR1BPTGS1HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7015322-B1 | Process for producing carbamazepine | DEGUSSA AG (DE) | 2006-03-21 | — | — | US | disclosed |
| EP-0277095-B2 | Method for preparing N,N-(dibenzohexatrienylene) ureas | NOVARTIS AG (CH) | 2001-09-05 | — | — | EP | disclosed |
| EP-0277095-B1 | METHOD FOR PREPARING N,N-(DIBENZOHEXATRIENYLENE) UREAS | Novartis AG (CH) | 1992-04-01 | — | — | EP | disclosed |