SCHEMBL586361

SCHEMBL586361

Nc1ncc(F)c(F)c1F

nearest known ligand 0.38

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ VRK1 Q99986 1/20 0.35
▸ AHCY P23526 8/20 0.33
▸ HTT P42858 1/20 0.32
▸ KMT2A Q03164 1/20 0.32
▸ NOS3 P29474 1/20 0.32
▸ NOS1 P29475 1/20 0.32
▸ NOS2 P35228 1/20 0.32
▸ SYK P43405 1/20 0.31
▸ BCL6 P41182 1/20 0.31
▸ ALDH1A1 P00352 1/20 0.30
▸ LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30503458 1.00 VRK1 (0.35) VRK1AHCYHTTKMT2ANOS3
SCHEMBL7361562 0.81 NOS3 (0.36) VRK1AHCYHTTKMT2ANOS3
SCHEMBL2222027 0.77 NOS3 (0.38) VRK1AHCYNOS3NOS1NOS2
SCHEMBL31489845 0.77 HTT (0.38) VRK1AHCYHTTKMT2ABCL6
SCHEMBL2326842 0.77 VRK1 (0.32) VRK1AHCY
SCHEMBL24007942 0.77 DAO (0.33) VRK1AHCY
SCHEMBL30414043 0.77 VRK1 (0.32) VRK1AHCY
SCHEMBL31358314 0.77 VRK1 (0.32) VRK1AHCY
SCHEMBL11712534 0.77 VRK1 (0.44) VRK1AHCY
SCHEMBL15624409 0.77 ALOX5AP (0.31) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 164 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119969414-A Sterilization composition for preventing and treating tomato fungal diseases and application thereof 河北省农林科学院植物保护研究所 2025-05-13 — — CN claimed
CN-119896226-A Novel pesticide composition with low residue and high activity 阳城县赵氏农牧发展有限公司 2025-04-29 — — CN claimed
CN-119744869-A Nematicidal composition and method for preventing and controlling nematodes 江苏功成生物科技有限公司 2025-04-04 — — CN claimed
CN-119699359-A Low-residue synergistic pesticide composition 四川易宏欣农业科技有限公司 2025-03-28 — — CN claimed
CN-119498343-A Sterilization composition for preventing and treating fig rust disease 广西壮族自治区农业科学院 2025-02-25 — — CN claimed
CN-119073312-A Sterilization composition for preventing and treating anthracnose of avocado 广西南亚热带农业科学研究所 2024-12-06 — — CN claimed
CN-118955201-A Granular special pesticide fertilizer and preparation method and application thereof 深圳诺普信作物科学股份有限公司 2024-11-15 — — CN claimed
CN-118923677-A Pesticide composition for preventing and treating pine wood nematode disease and application thereof 海南利蒙特生物科技有限公司 2024-11-12 — — CN claimed
CN-118844447-A Agricultural insecticidal composition and application thereof 青岛滨海泰生作物科学有限公司 2024-10-29 — — CN claimed
CN-118680180-A Application of SDHI bactericide or biocontrol bacterium combination in prevention and treatment of fusarium oxysporum 海峡两岸农业科技股份有限公司 2024-09-24 — — CN claimed
CN-117859770-A Biological microcapsule preparation and application thereof 河南省农业科学院植物保护研究所 2024-04-12 — — CN claimed
CN-117813005-A Fungicidal compositions 先正达农作物保护股份公司 2024-04-02 — — CN claimed
CN-117751941-A Nematicidal composition containing trifluoropyridinamine and abamectin and application thereof 浙江威昇作物科技有限公司 2024-03-26 — — CN claimed
CN-117413826-A Nanometer emulsion preparation containing trifluoropyridinamine and preparation method thereof 广东真格生物科技有限公司 2024-01-19 — — CN claimed
CN-117320551-A Seed treatment composition 先正达农作物保护股份公司 2023-12-29 — — CN claimed
CN-117320552-A Insect, acarina and nematode pest control 先正达农作物保护股份公司 2023-12-29 — — CN claimed
CN-116801720-A Novel agrochemical compositions comprising 3-substituted benzamidine compounds and uses thereof 皮埃企业有限公司 2023-09-22 — — CN claimed
CN-116744794-A Fungicidal compositions 先正达农作物保护股份公司 2023-09-12 — — CN claimed
CN-116634867-A Method for controlling or preventing infestation of plants by phytopathogenic microorganisms of the genus Aspergillus 先正达农作物保护股份公司 2023-08-22 — — CN claimed
CN-116473062-A Sterilization composition for preventing and treating passion fruit stem basal rot 广西壮族自治区亚热带作物研究所(广西亚热带农产品加工研究所) 2023-07-25 — — CN claimed
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